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PI Physik Instrumente - Revolution In Photonics Align ROSLB 3/24

Probes Enhance Microscopy

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Kevin Robinson

Researchers at Max Planck Institut für Biochemie in Martinsried, Germany, have developed a probe design that improves the resolution of near-field scanning optical microscopes. The tip-on-aperture probes combine the benefits of aperture and apertureless probes, and they promise high optical and topographic resolution with low background noise. A new probe for use in near-field scanning optical microscopy combines the benefits of aperture and apertureless designs. Courtesy of Heinrich G. Frey. Near-field scanning optical microscopy overcomes the diffraction limit in conventional optics...Read full article

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    Published: February 2003
    Glossary
    probe
    Acronym for profile resolution obtained by excitation. In its simplest form, probe involves the overlap of two counter-propagating laser pulses of appropriate wavelength, such that one pulse selectively populates a given excited state of the species of interest while the other measures the increase in absorption due to the increase in the degree of excitation.
    resolution
    1. In optics, the ability of a lens system to reproduce the points, lines and surfaces in an object as separate entities in the image. 2. The minimum adjustment increment effectively achievable by a positioning mechanism. 3. In image processing, the accuracy with which brightness, spatial parameters and frame rate are divided into discrete levels.
    Basic Sciencediffraction limitMicroscopyoptical microscopesprobeResearch & TechnologyresolutionTech Pulsetopographic resolution

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