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SD-OCT Could Help Nip Cancer in the Bud

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Kipp Lynch, PhD

PRINCETON, N.J., March 16, 2007 -- Spectral domain optical coherence tomography (SD–OCT) in human tissue is demonstrating exciting capability to detect precancerous changes to cells years before tumors develop. SD-OCT can probe 3 mm into tissue -- skin, throat, colon or cardiovascular -- with microscope resolution of 10 µm. Doug Malchow, manager of commercial business development at Princeton, N.J.-based Sensors Unlimited Inc. (SUI), contrasts this technique to his early school days. “I remember the dramatic images in high-school biology when you took a stained tissue histology slide and looked at it under the microscope...Read full article

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    Published: March 2007
    Glossary
    photonics
    The technology of generating and harnessing light and other forms of radiant energy whose quantum unit is the photon. The science includes light emission, transmission, deflection, amplification and detection by optical components and instruments, lasers and other light sources, fiber optics, electro-optical instrumentation, related hardware and electronics, and sophisticated systems. The range of applications of photonics extends from energy generation to detection to communications and...
    spectral domain optical coherence tomography
    Spectral domain optical coherence tomography is an imaging technique used in medical diagnostics, particularly in ophthalmology, to visualize and analyze the internal structures of biological tissues, most commonly the retina in the eye. Key concepts in SD-OCT are: Optical coherence tomography (OCT): OCT is a non-invasive imaging technique that uses low-coherence interferometry to obtain high-resolution, cross-sectional images of biological tissues. It works by measuring the echo time delay...
    BiophotonicsDoug MalchowMicroscopyNews & Featuresphotonicsprecancerous changes to cellsSD-OCTSD–OCTSensors & DetectorsSensors UnlimitedSpectral domain optical coherence tomographySUI

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