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CARS Reveals Myelin Clues

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WEST LAFAYETTE, Ind., June 27, 2007 -- A new imaging technique called coherent anti-Stokes Raman scattering, or CARS, has lead to the discovery that calcium ions could play a crucial role in multiple sclerosis (MS) by activating enzymes that degrade myelin, the fatty sheath that insulates nerve fibers. This unprecedented feat of looking real-time at the actual progress of demyelination will advance understanding of and perhaps promote early detection of conditions such as MS in which the myelin sheath has been found to degrade. Learning exactly how the myelin sheath is degraded might enable scientists to determine how to halt...Read full article

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    Published: June 2007
    Glossary
    coherent anti-stokes raman scattering
    A technique whereby two laser beams, one at an excitation wavelength and the second at a wavelength that produces Stokes Raman scattering, interact coherently in a sample, producing a strong scattered beam at the anti-Stokes wavelength.
    photonics
    The technology of generating and harnessing light and other forms of radiant energy whose quantum unit is the photon. The science includes light emission, transmission, deflection, amplification and detection by optical components and instruments, lasers and other light sources, fiber optics, electro-optical instrumentation, related hardware and electronics, and sophisticated systems. The range of applications of photonics extends from energy generation to detection to communications and...
    Basic ScienceBiophotonicscalcium ionsCARScoherent anti-Stokes Raman scatteringimaging techniqueindustrialMicroscopyMSmultiple sclerosismyelinmyelin sheathNews & FeaturesphotonicsPurdue University

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