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Optically tracking transmissions in the brain

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Researchers improve a genetically expressed glutamate-sensitive reporter.

Hank Hogan

Scientists researching the many mechanisms behind learning, memory and other activities of the brain have a new tool that promises to enable tracking of some of the most basic processes. It eventually could help unravel some of the mysteries of thought. A group at the University of California, San Diego, in La Jolla, developed a new genetically expressed glutamate-sensitive fluorescent reporter. They dubbed it SuperGluSnFR because it’s an optimized version of the group’s original GluSnFR glutamate-sensing fluorescent reporter. The new version exhibits a 6.2-fold increase in response...Read full article

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    Published: May 2008
    BiophotonicsenergyGluSnFRglutamate-sensitive fluorescentmechanismsResearch & TechnologySensors & Detectors

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