Part of the “Bioinformatics & Biomedical Imaging” series, the 511-page book Microscopic Image Analysis for Life Science Applications details imaging platforms, fluorescence imaging and fundamental image processing algorithms. Applications ranging from the detection of signaling events in subcellular structures to the automated analysis of tissue structures are presented. A companion CD-ROM contains images and videos to further illustrate the topics discussed. Jens Rittscher, Raghu Machiraju, and Stephen T.C. Wong, eds.; Artech House, Norwood, Mass., 2008; $159.