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Automated, 3-D, submicron-resolution imaging of C. elegans

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David L. Shenkenberg

The tiny, transparent roundworm, Caenorhabditis elegans, has proved a useful research model. Consisting of fewer than 1000 cells, it is relatively simple to study, yet 60 percent to 80 percent of human and C. elegans genes are derived from common evolutionary ancestors. Furthermore, C. elegans research has garnered two Nobel Prizes in physiology and medicine in the past five years, one for studies of organogenesis and programmed cell death and the other for demonstration of the RNA interference mechanism. The worms can enable studies of other genetic pathways shared with humans, such as...Read full article

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    Published: November 2007
    Biophotonicsgenetic pathwaysindustrialMicroscopyneurodegenerative disordersResearch & Technologytherapeutic

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