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Early Cancer Detection with Fluorophores That Target the Folate Receptor

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Researchers use targeted fluorophores for flow cytometry in clinical trials and for optical imaging in living mice.

David L. Shenkenberg, Associate News Editor

All it takes is one tumor cell circulating through the bloodstream to turn a manageable tumor into metastatic disease, and just one tumor cell can cause cancer to recur in patients who have received treatment. Although high-resolution clinical imaging methods such as CT and MRI can detect masses much smaller than 1 cm, they cannot identify an individual tumor cell. Flow cytometry of blood samples can detect tumor cells that were circulating in patients, but blood samples represent only a small fraction of a patient’s blood. For example, blood makes up about 7 percent of the body, so a 5-ml...Read full article

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    Published: October 2007
    BiophotonicsCTFeaturesMicroscopyMRIoptical imaging

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