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FISH-ing for cancer just got easier

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Fluorescence in situ hybridization (FISH) can detect chromosomal mutations that cause cancer, but the technique can take days to perform and cost hundreds of dollars. Consequently, the method is not yet widely used in clinical settings. However, researchers from the University of Alberta and from Cross Cancer Institute, both in Edmonton, Canada, integrated the technique into a microfluidics chip, enabling the test to run in just hours at a cost of only tens of dollars. This fluorescence image shows a microchannel within a microfluidics chip after FISH was performed. Additionally, the...Read full article

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    Published: July 2007
    Glossary
    fluorescence
    Fluorescence is a type of luminescence, which is the emission of light by a substance that has absorbed light or other electromagnetic radiation. Specifically, fluorescence involves the absorption of light at one wavelength and the subsequent re-emission of light at a longer wavelength. The emitted light occurs almost instantaneously and ceases when the excitation light source is removed. Key characteristics of fluorescence include: Excitation and emission wavelengths: Fluorescent materials...
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