Close

Search

Search Menu
Photonics Media Photonics Buyers' Guide Photonics EDU Photonics Spectra BioPhotonics EuroPhotonics Industrial Photonics Photonics Showcase Photonics ProdSpec Photonics Handbook
More News
SPECIAL ANNOUNCEMENT
2016 Photonics Buyers' Guide Clearance! – Use Coupon Code FC16 to save 60%!
share
Email Facebook Twitter Google+ LinkedIn Comments

Sandia National Laboratories

BioPhotonics
May 2007
Researchers at Sandia National Laboratories in Albuquerque, N.M., have begun imaging-based studies in the context of an immunological research project. The University of Texas Medical Branch in Galveston and the University of California, San Francisco, are cooperating with Sandia on the Microscale Immune Studies Laboratory Grand Challenge. In the current investigation, the scientists will seek to elucidate the response of individual immune cells — rather than large populations of cells — to pathogens in the first minutes and hours of exposure. To accomplish this, the team will employ a platform with two complementary microfluidic modules. The first module traps and images cells while they are stimulated by pathogens. The other prepares, selects and sorts cells, then examines their protein content using hyperspectral fluorescence imaging with multivariate curve resolution. The investigators aim to conduct 3-D quantitative analysis of 10 to 40 proteins and cellular strains at a time with the system. Computer modeling will be used to develop network models from the experimental data. The results may be used to find better ways to diagnose disease and to develop improved thera-pies. The project is in its second of three years of funding by Sandia’s Laboratory Directed Research and Development program.


Comments
Terms & Conditions Privacy Policy About Us Contact Us
back to top

Facebook Twitter Instagram LinkedIn YouTube RSS
©2016 Photonics Media
x Subscribe to BioPhotonics magazine - FREE!