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Perkins Precision Developments - Plate Polarizers LB 4/24

University of California

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The University of California, San Francisco, has given Carl Zeiss MicroImaging GmbH a license to commercialize a superresolution microscopy technique developed by scientists at the university. Called structured illumination microscopy, the method combines a special illumination pattern with state-of-the-art computational image analysis to produce images with up to double the resolution in all three spatial directions in comparison to those taken with conventional microscopes. The agreement grants the company the right to integrate the technique into its microscope systems.
PowerPhotonic Ltd. - Coherent Beam 4/24 MR

Published: February 2010
Glossary
illumination
The general term for the application of light to a subject. It should not be used in place of the specific quantity illuminance.
microscope
An instrument consisting essentially of a tube 160 mm long, with an objective lens at the distant end and an eyepiece at the near end. The objective forms a real aerial image of the object in the focal plane of the eyepiece where it is observed by the eye. The overall magnifying power is equal to the linear magnification of the objective multiplied by the magnifying power of the eyepiece. The eyepiece can be replaced by a film to photograph the primary image, or a positive or negative relay...
structured illumination microscopy
Structured illumination microscopy (SIM) is an advanced optical imaging technique used in microscopy to enhance the resolution of images beyond the diffraction limit imposed by traditional light microscopy. The diffraction limit is a fundamental limitation that restricts the ability to distinguish fine details in the microscopic structures. SIM achieves improved resolution through a process of illuminating the specimen with a patterned light, typically a grid or a stripe pattern. This...
superresolution
Superresolution refers to the enhancement or improvement of the spatial resolution beyond the conventional limits imposed by the diffraction of light. In the context of imaging, it is a set of techniques and algorithms that aim to achieve higher resolution images than what is traditionally possible using standard imaging systems. In conventional optical microscopy, the resolution is limited by the diffraction of light, a phenomenon described by Ernst Abbe's diffraction limit. This limit sets a...
system
A combination of components arranged so as to perform at least one function.
BiophotonicsBusinessCarl ZeissCarl Zeiss MicroImagingilluminationImage AnalysisImagingmicroscopeMicroscopyOpticsRapidScanspatialstructured illumination microscopysuperresolutionsuperresolution microscopysystemUniversity of California

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