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Lensless Microscope Made for Telemedicine

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LOS ANGELES, April 27, 2010 — Aydogan Ozcan, whose invention of a novel lensless imaging technology for telemedicine could radically transform global health care, has now taken his work a step further. The University of California, Los Angeles engineer has created a miniature microscope, the world's smallest and lightest for telemedicine applications. The microscope, unveiled in a paper published online in the journal Lab on a Chip, builds on imaging technology known as LUCAS (Lensless Ultrawide-field Cell Monitoring Array platform based on Shadow imaging), which was developed by Ozcan, who is an assistant professor...Read full article

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    Published: April 2010
    Glossary
    differential interference contrast microscopy
    Differential interference contrast (DIC) microscopy, also known as Nomarski interference contrast microscopy, is an optical imaging technique used in microscopy to enhance the contrast of transparent and colorless specimens. DIC microscopy provides three-dimensional, relief-like images by exploiting the interference of polarized light. Key features and principles of differential interference contrast microscopy include: Polarized light: DIC microscopy uses polarized light to enhance image...
    holography
    Holography is a technique used to capture and reconstruct three-dimensional images using the principles of interference and diffraction of light. Unlike conventional photography, which records only the intensity of light, holography records both the intensity and phase information of light waves scattered from an object. This allows the faithful reproduction of the object's three-dimensional structure, including its depth, shape, and texture. The process of holography typically involves the...
    microscope
    An instrument consisting essentially of a tube 160 mm long, with an objective lens at the distant end and an eyepiece at the near end. The objective forms a real aerial image of the object in the focal plane of the eyepiece where it is observed by the eye. The overall magnifying power is equal to the linear magnification of the objective multiplied by the magnifying power of the eyepiece. The eyepiece can be replaced by a film to photograph the primary image, or a positive or negative relay...
    AmericasAydogan OzcanBasic Scienceblood samplesCaliforniaCalifornia NanoSystems InstitutecellsDIC microscopydifferential interference contrast microscopyglobal health careholographyImaginglab on a chiplenseslensless imagingLight SourcesLUCASmicroscopeMicroscopyNomarski microscopeOpticsResearch & TechnologySensors & DetectorstelemedicineUCLALEDs

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