Search Menu
Photonics Media Photonics Buyers' Guide Photonics EDU Photonics Spectra BioPhotonics EuroPhotonics Industrial Photonics Photonics Showcase Photonics ProdSpec Photonics Handbook
More News
Email Facebook Twitter Google+ LinkedIn Comments

  • Luciferase Aids Blood Clot Detection
Feb 2011
NEW LONDON, Conn., Feb. 11, 2011 — The enzyme that makes fireflies glow is lighting up the scientific path toward a long-sought new medical imaging agent to better monitor treatment with heparin, the blood thinner that millions of people take to prevent or treat blood clots.

In a study appearing in the journal Bioconjugate Chemistry, Bruce Branchini of Connecticut College and his colleagues describe a need for new medical imaging agents that emit near-infrared light – the light rays that "night vision" technology detects, enabling soldiers to see in the dark. Those rays penetrate deeper into the body and could give doctors a better way of detecting the proteins involved in blood clotting. Scientists already use luciferase, the enzyme that makes lightning bugs glow, in laboratory research.

The new study describes an advance toward using luciferase in medical imaging. The scientists combined a protein obtained from firefly luciferase with a special dye that allows the protein to emit near-infrared light. In laboratory experiments, the new material successfully detected minute amounts of a specific blood protein, called factor Xa, which is used to monitor the effectiveness of heparin treatment. It offers promise for improved monitoring of heparin therapy, the article suggests.

For more information, visit: 

Terms & Conditions Privacy Policy About Us Contact Us
back to top

Facebook Twitter Instagram LinkedIn YouTube RSS
©2016 Photonics Media
x We deliver – right to your inbox. Subscribe FREE to our newsletters.