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World’s fastest camera takes on biosensing

BioPhotonics
Feb 2011
TEDDINGTON, UK – A new ultrafast camera will have applications in biological processes as well as automotive collisions and astronomical observations. The Megaframe Imager can record images at 1 million fps, far faster than the normal video rate of 24 fps.

But thanks to a single-photon avalanche diode device and bespoke on-chip intelligence, higher-than-video speeds are achievable, which opens up a new range of previously unthinkable applications, from cellular and subcellular imaging to neural imaging, from biochemical sensors and DNA/protein microarray scanning, to automotive collision studies and even highly sensitive astronomical observations.

The camera was developed by a European consortium made up of the National Physical Laboratory, ST Microelectronics, the University of Edinburgh and TU Delft. The research team has reported detection of viral DNA binding events using fluorescence lifetime imaging at low target concentrations, needed for biosensing applications. The acquisition times in the current study were less than 30 seconds.

The results were reported in the Optical Society of America’s new journal Biomedical Optics Express, Vol. 1, Issue 5, pp. 1302-1308 (2010).


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