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Supermicroscope Pinpoints Body’s Immunity “Switch”

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SYDNEY, Australia, June 6, 2011 — Superresolution fluorescence microscopy has provided a glimpse into the inner workings of T cells, the front-line troops that alert our immune system to go on the defensive against germs and other invaders in our bloodstream. The discovery identified the exact molecular switch that spurs T cells into action — a breakthrough that could lead to treatments for conditions ranging from autoimmune diseases to cancer. Studying a cell protein that is important in early immune response, researchers at the University of New South Wales (UNSW) used Australia’s only superresolution...Read full article

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    Published: June 2011
    Glossary
    superresolution
    Superresolution refers to the enhancement or improvement of the spatial resolution beyond the conventional limits imposed by the diffraction of light. In the context of imaging, it is a set of techniques and algorithms that aim to achieve higher resolution images than what is traditionally possible using standard imaging systems. In conventional optical microscopy, the resolution is limited by the diffraction of light, a phenomenon described by Ernst Abbe's diffraction limit. This limit sets a...
    Asia-PacificAustraliaBiophotonicsImagingimmune systemKatharina GausMicroscopyResearch & Technologysuperresolutionsuperresolution fluorescence microscopyT cellsUniversity of New South Wales

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