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Terahertz Techniques Reveal the Hidden World of Pharmaceuticals

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Lynn Savage, Features Editor, [email protected]

Advances in terahertz imaging and spectroscopy are making it easier for pharmaceutical researchers and manufacturers to predict crystal structures of common and uncommon drugs as well as to distinguish among drug polymorphs. For a little more than a decade, the pharmaceuticals industry has gradually adopted terahertz-based technology – especially as more manufacturers enter the field and offer their own improvements – but there remains a lack of clear understanding about the interactions between terahertz radiation and the organic molecules that comprise active pharmaceutical...Read full article

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    Published: February 2012
    Glossary
    absorption
    The transfer of energy from an incident electromagnetic energy field with wavelength or frequency to an atomic or molecular medium.
    x-ray crystallography
    The study of the arrangement of atoms in a crystal by means of x-rays.
    absorptionAlfred UniversityBasic ScienceBiophotonicsbronchodilatorsCaliforniachemicalschronic obstructive pulmonary diseaseCoatingsCoherent Inc.COPDcreatinecrystal lattice featuresDaiichi Sankyo Ltd.diclofenac aciddistributionDPSS lasersEastman Kodak Co.excretionFeaturesImagingindustrialJapanmetabolismNd:YLF lasersNd:YVO4 lasersNSAIDsorganic moleculepharmaceutical quality controlpharmaceuticalspolymorphsPositive Lightpseudopolymorphssolid-state density functional theoryspectroscopySyracuse Universitytablet coatingsterahert spectroscopyterahertz imagingtheophyllineTi:sapphire lasersTimothy M. KorterTochigi Nikon Corp.Toho Universityx-ray crystallographyzinc tellurideLasers

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