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Zeiss microscopy technology gets European patent

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Drs. Harald Hess and Eric Betzig of Jena, Germany-based Carl Zeiss Microscopy have received a European patent for their superresolution photoactivated localization microscopy technology. They received US patents in 2009 and 2011 based on the same invention. The patent protects methods and devices for photoactivated localization microscopy, which activates and excites only a small number of fluorescent dye molecules in a sample at a time, enabling the physical position of the individual fluorescent molecules to be determined to within a few nanometers. A superresolution image of the sample is generated by repeating a photoinduced separation of fluorescent dye molecules and adding consecutively captured individual images.
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Published: May 2013
Glossary
superresolution
Superresolution refers to the enhancement or improvement of the spatial resolution beyond the conventional limits imposed by the diffraction of light. In the context of imaging, it is a set of techniques and algorithms that aim to achieve higher resolution images than what is traditionally possible using standard imaging systems. In conventional optical microscopy, the resolution is limited by the diffraction of light, a phenomenon described by Ernst Abbe's diffraction limit. This limit sets a...
BiophotonicsBusinessCarl Zeiss MicroscopyEric BetzigHarald HessMicroscopypatentRapidScansuperresolutionZeiss

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