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Imaging Technology Could Unlock Mysteries of a Childhood Disease

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A superresolution imaging technique that allows the structure of a respiratory virus to be seen in living cells could help unlock the virus's secrets, including how it enters cells and replicates, and why certain lung cells escape relatively unscathed. By the time children turn 2, most have had respiratory syncytial virus (RSV), and suffered coldlike symptoms. But for some, especially premature babies and the sick, the virus can be much more serious, leading to pneumonia and bronchitis. A superresolution optical image of a specific hRSV viral filament produced with dSTORM...Read full article

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    Published: January 2014
    Glossary
    superresolution
    Superresolution refers to the enhancement or improvement of the spatial resolution beyond the conventional limits imposed by the diffraction of light. In the context of imaging, it is a set of techniques and algorithms that aim to achieve higher resolution images than what is traditionally possible using standard imaging systems. In conventional optical microscopy, the resolution is limited by the diffraction of light, a phenomenon described by Ernst Abbe's diffraction limit. This limit sets a...
    Americasantiviral drugsantiviral vaccineBiophotonicsBioScanDNAdSTORM imagingebolafluGeorgiaGeorgia Techgold nanoparticlesImagingMicroscopyMTRIPSmultiply labeled tetravalent RNA imaging probesPhilip SantangeloResearch & Technologyrespiratory syncytial virusRSVsuperresolutionsuperresolution imagingVanderbilt University

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