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Light Triggers Stem Cell Differentiation

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Blue light can trigger the transformation of embryonic stem cells into neurons. Based on optogenetics techniques, the discovery could be a first step toward complex tissue engineering using light, according to researchers at the University of California, San Francisco. "There's lots of promise that we can do these miraculous things like tissue repair or even growing new organs," said faculty fellow Matthew Thomson, "but in practice, manipulating stem cells has been notoriously noisy, inefficient and difficult to control. "I think it's because the cell is not a puppet. It's...Read full article

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    Published: August 2015
    Glossary
    optogenetics
    A discipline that combines optics and genetics to enable the use of light to stimulate and control cells in living tissue, typically neurons, which have been genetically modified to respond to light. Only the cells that have been modified to include light-sensitive proteins will be under control of the light. The ability to selectively target cells gives researchers precise control. Using light to control the excitation, inhibition and signaling pathways of specific cells or groups of...
    BiophotonicsResearch & TechnologyAmericasCaliforniaUniversity of CaliforniaSan FranciscoUCSFMatthew Thomsonoptogeneticsstem cellstissue engineeringCRISPRTech PulseBioScan

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