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Feedback Provides Better Optogenetics Control

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Feedback control could give optogenetics the specificity it needs to fight neurological disorders like epilepsy, chronic pain and depression. Neural stimulation systems based on electrical inputs already use feedback to control to fine tune their effects, but a device developed at the Georgia Institute of Technology is the first to provide similar control for optical stimulation. Georgia Tech doctoral student Riley Zeller-Townson demonstrates preparation of a cell culture for placement into the optoclamp. Courtesy of Rob Felt/Georgia Tech. "Our work establishes a versatile test...Read full article

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    Published: September 2015
    Glossary
    optogenetics
    A discipline that combines optics and genetics to enable the use of light to stimulate and control cells in living tissue, typically neurons, which have been genetically modified to respond to light. Only the cells that have been modified to include light-sensitive proteins will be under control of the light. The ability to selectively target cells gives researchers precise control. Using light to control the excitation, inhibition and signaling pathways of specific cells or groups of...
    Research & TechnologyAmericasGeorgiaGeorgia TechEmory UniversityoptogeneticsSteve PotterJon NewmanBiophotonicsoptoclampBioScan

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