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Advances in Laser Diodes Can Bring Portability to Point-of-Care Photoacoustic Systems

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Today’s aging population faces an increase in chronic afflictions such as rheumatoid arthritis, cancer and cardiovascular disease. Photoacoustics is a novel imaging technique that could help monitor disease at an early stage, providing structural and functional information of blood vessels and tissues. Efforts are underway to drastically shrink the size of existing photoacoustic imaging systems by developing highly efficient ultra-short pulse emission near infrared laser diodes.

CELINE CANAL AND ANDREAS KOHL, QUANTEL

Photoacoustic imaging (PAI) has attracted much attention in recent years as a complementary technique to classical ultrasound and optical coherence tomography. This novel technique combines pulsed laser light for excitation of tissues with an ultrasound transducer as a receptor. PAI penetrates deeper than pure optical imaging technologies, such as optical coherence tomography, and offers far greater specificity than conventional ultrasound imaging. PAI has the ability to detect hemoglobin, lipids, water and other light-absorbing chromophores by changing the laser source wavelength. In...Read full article

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    Published: February 2016
    Glossary
    photoacoustic imaging
    Abbreviated PAI. An imaging modality with a hybrid technique based on the acoustic detection of optical absorption from endogenous chromophores or exogenous contrast agents. Light is absorbed by the chromophores and converted into transient heating, and through thermoelastic expansion there is a resulting emission of ultrasonic waves. In tissue, ultrasound scatters less than light, therefore PAI generates high-resolution images in the diffusive and optical ballistic regimes compared to purely...
    optical coherence tomography
    Optical coherence tomography (OCT) is a non-invasive imaging technique used in medical and scientific fields to capture high-resolution, cross-sectional images of biological tissues. It provides detailed, real-time, and three-dimensional visualization of tissue structures at the micrometer scale. OCT is particularly valuable in ophthalmology, cardiology, dermatology, and various other medical specialties. Here are the key features and components of optical coherence tomography: Principle of...
    BiophotonicsFeaturespulsed lasersphotoacoustic imagingPAImedical imagingEuropeQuanteloptical coherence tomographyuntrasoundPoint-of-carePOCNd:YAG lasersoptical parametric oscillatorslaser fiodesphotoacoustic scannerCeline CanalAndreas KohlLasers

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