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Mirror-Enhanced Microscopy Captures Cell Behaviors

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A novel technique for growing cells on miniature mirrors and imaging them using super-resolution microscopy may provide a way to view cell structures at a micron scale. The technique uses light waves to create interference patterns as light passes through the cell on the way to the mirror, which reflects the light back through the cell. Researchers Phil Santangelo and Eric Alonas are shown with a spinning disk confocal microscope used to image cells. Santangelo is a professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University; Alonas is a...Read full article

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    Published: July 2016
    Glossary
    superresolution
    Superresolution refers to the enhancement or improvement of the spatial resolution beyond the conventional limits imposed by the diffraction of light. In the context of imaging, it is a set of techniques and algorithms that aim to achieve higher resolution images than what is traditionally possible using standard imaging systems. In conventional optical microscopy, the resolution is limited by the diffraction of light, a phenomenon described by Ernst Abbe's diffraction limit. This limit sets a...
    BiophotonicsmirrorsResearch & TechnologysuperresolutionAsia-PacificAmericasPeking UniversityGeorgia Institute of TechnologyUniversity of Technology SydneyMicroscopyOpticssuper-resolutionImagingBioScan

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