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New Spectrometer Sheds Light on Chemical Mystery

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Susanna Contini Hennink

GLASGOW, UK -- Determining the absolute configuration of molecules is a prerequisite to developing new medicines. So-called chiral molecules are common and yet complex entities, existing in two forms that are mirror images of one another. Among the simplest of them is bromochlorofluoromethane (CHFClBr), which has hidden the relationship between its three-dimensional structure and the sign of its optical rotation -- until now. A collaboration among scientists in France, Scotland and the US has established the absolute configuration of CHFClBr, thanks in part to a Raman optical activity...Read full article

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    Published: August 1997
    Research & TechnologyspectroscopyTech Pulse

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