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BioPhotonics: April 2015

Advances in Optical Filters Provide Rapid, On-the-Go Diagnosis
When it comes to diagnostics, one of the most crucial – and often overlooked – components is the optical filter. But as manufacturing processes improve, optical filters of exceptional...
Marie Freebody, Contributing Editor,
Comparing Micromanipulators for Electrophysiology
Several different technologies offer a range of performance options within the confines of an optical microscope for patch-clamp studies, intracellular recording and other demanding experiments in...
John Wingerd, Siskiyou Corporation
Focus-Tunable Lenses Enable 3-D Microscopy
Focus-tunable lenses speed up and enhance three-dimensional imaging capabilities in a diverse set of modern microscopy methods including confocal, two-photon and light-sheet microscopy. ...
David Leuenberger, Optotune AG, and Fabian F. Voigt, University of Zurich
Lasers for Microscopy: Major Trends
Laser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...
Marco Arrigoni, Nigel Gallaher, Darryl McCoy, Volker Pfeufer and Matthais Schulze, Coherent Inc.

Improving Diagnosis for Better Resolution
Conclusively identifying illness is job one for physicians, who rely on a variety of medical devices, along with an evaluation of signs and symptoms, to determine just what’s ailing patients. Diagnostic tools introduced through the centuries have ranged from microscopes and stethoscopes to thermometers and x-ray imaging and more, which have contributed greatly to modern health care. For...
Karen A. Newman, Group Publisher,

Microscope Takes 3-D Images From Inside Moving Subjects
A new kind of microscope enables rapid 3-D imaging of living and moving samples, potentially offering advantages over laser-scanning confocal, two-photon and light-sheet microscopy. Developed by Columbia University professor Dr. Elizabeth Hillman and graduate student Matthew Bouchard, swept confocally aligned planar excitation (SCAPE) microscopy involves simplified equipment and does not...
Fluorometer Measures Glucose Levels Noninvasively
A new light-based diagnostic tool allows physicians to monitor blood sugar levels in patients who can’t give blood samples. The Glucolight system is intended to help prevent...
Expanded Tissues Can Be Seen Through Confocal Microscopes
Nobel Prize-winning superresolution microscopy techniques circumvent the diffraction limit of light to image the smallest details of cells. But there is another way. Researchers at MIT have...
Fluorescent Label Aids Whole-Brain Imaging In Vivo
A new permanent fluorescent label allows researchers to study complex neural activity in wide swaths of brain tissue in moving animals. Developed at the Howard Hughes Medical Institute, the...
Cubic Nanoantennas Eyed for NEMS Biosensors
Lab-on-a-chip applications could benefit from cubic nanoantennas that direct light more effectively than spherical ones. The cubes, which are composed of insulating rather than conducting or...

LIA, OSHA Renew Laser Safety Alliance
The U.S. Occupational Safety and Health Administration (OSHA) and the Laser Institute of America (LIA) have renewed their partnership to help protect workers from exposure to laser hazards. ...
Shanghai Investors Increase Stake in LightPath Technologies
LightPath Technologies Inc. plans to use a $1.3 million investment to support new product development, sales and marketing of its IR products and the acquisition of new equipment. The...
Viso Systems, Acal BFi Extend Partnership
Viso Systems of Copenhagen, Denmark, will distribute Acal BFi products in France, Italy, Spain and the U.K. The companies have had a distribution agreement for the last two years covering...
In Memoriam: Charles Hard Townes
Dr. Charles Hard Townes, whose work on stimulated emission led to the creation of lasers and enabled the photonics industry, died Jan. 27 at age 99. Townes won the 1964 Nobel Prize in Physics...
JPK Opens Expanded Headquarters
Citing growing demand for its nanoanalytics products, JPK Instruments has moved into an expanded suite of offices and laboratories with increased manufacturing space. The company offers...
Companies To Develop IR Glass-Molded Optics
Edmund Optics Inc. and Fisba Optik LLC of Tucson, Ariz., have teamed up to produce IR optics using nontraditional materials. The new components will be suited for life sciences applications...
Newport Acquires Femtolasers, Touts Record Sales
Newport Corp. notched sales and orders records in 2014, with profits reaching $35.1 million. Net sales for the year were $605.2 million, $158.7 million of that coming in the fourth quarter. ...
Earnings Jump at Hamilton Thorne
Biophotonics firm Hamilton Thorne Ltd. said it experienced a five-fold increase in profits from 2013 to 2014. Preliminary figures put net income at more than $800,000, compared to $125,000...

The Optical Nature of Yellowstone’s Pools
Visitors from around the world view with awe the stunning colors of thermal pools in Yellowstone National Park, situated primarily in Wyoming and extending into Montana and Idaho. The brilliant hues of these natural wonders – Morning Glory Pool, Sapphire Pool, Grand Prismatic Spring and others – have engaged the curiosity of Dr. Joseph Shaw, professor at Montana State University and...

Optical Pulse Oximeter
The Reflective Pulse Oximetry Sensor from Taiwan Biophotonic Co. is designed to be worn comfortably on the wrist rather than the fingers, toes or earlobes. The device measures pulse rate and...
Scientific CMOS Camera
The Dhyana 400A scientific CMOS camera from Xintu Photonics Co. Ltd. offers a 93-dB dynamic range, a 25 fps frame rate and a readout noise of 1.5 electrons. The camera is suited for ultralow...
Xintu Photonics Co., Ltd. (Tucsen)
Femtosecond Laser
The Origami-XP from Onefive GmbH is an air-cooled microjoule femtosecond laser. It provides flexible repetition rates from single-shot to 1 MHz, 60-µJ pulse energy, 4-W average power,...
Onefive GmbH
Camera, Sensor Calibration
The CCS-1000 systems from Labsphere are a series of uniform LED light sources for camera and sensor calibration. Standard sources like illuminant A, B, C, D50, 55, 65, 75, F2 and F12 are set...
Labsphere, Inc., Photonics
IR Detectors
CalSensors’ SCD-B line of photodetectors are optimized to provide the high performance of lead salt detectors while reducing harmful radiation. Sensitive across the mid-infrared...
Opto Diode Corporation
Quantum Cascade Laser
The quantum cascade laser (QCL) series from Wavelength Electronics feature low-noise drive electronics for lower detection thresholds. Possible output currents of 500, 1000, 1500, and 2000...
Wavelength Electronics, Inc.
Confocal Microscope
The LSM 800 from Zeiss is a compact confocal laser-scanning microscope for high-end confocal imaging. The microscope features Airyscan computer-aided phase capabilities. Its gallium...
Carl Zeiss Microscopy GmbH, Electron- and Ion-Beam Microscopes
Laser Diodes
ProPhotonix is distributing a new line of laser diodes from Panasonic. The red (661 nm) and IR (783 nm) single-mode, 5.6-mm can-packaged laser diodes are available with output powers of 100...
ProPhotonix Ltd.
A time-resolved Forster resonance energy transfer (TR-FRET) high-throughput screening assay from BellBrook Labs is designed for use with for UDP-producing enzymes. The device relies on...
BellBrook Labs
Industrial Camera
The newest Blackfly industrial camera from Point Grey features high-speed triggering and region-of-interest functionality. The BFLY-PGE-23S6 is based on a 2.3-MP Sony IMX249 Pregius...
Point Grey Research Inc.
Materials Processing Laser
The BlueCut fiber laser from Menlo Systems GmbH generates pulses at <400 fs with energies of 10 µJ and up to 10 W average power. The system offers a femtosecond burst mode feature...
Menlo Systems GmbH
Dual-Wavelength Laser
The latest dual-wavelength laser from Toptica Photonics Inc. is intended for two-photon excitation. The FemtoFiber dichro design bioMP offers two synchronized beams of different wavelengths...
TOPTICA Photonics, Inc.
Disposable-Fiber Laser
A 14-pin laser package from SemiNex Corp. is suited for integration as a high-power IR laser in systems where the use of disposable fibers is prevalent. The laser produces up to 5.8 W of CW...
SemiNex Corp.
Femtosecond Laser
Spectra-Physics has announced the Spirit One, a new femtosecond laser that enables advancement in high-precision applications. With ultrashort <400-fs pulse width, high pulse energy,...
Spectra-Physics Lasers Div., Laser Science
Remote Visual Inspection
Featuring a powerful LED source, the Techno Pack T LED from Karl Storz Industrial Group is a measuring and documentation system for the remote visual inspection market. When used in...
Karl Storz GmbH & Co. KG
SWIR Line-Scan Camera
A new 2k shortwave-infrared (SWIR) line-scan camera from Sensors Unlimited Inc. is designed for applications in spectral-domain optical coherence tomography (SD-OCT). The GL2048R is...
Sensors Unlimited - UTC Aerospace Systems
UV Crosslinker
A UV crosslinker from Spectronics Corp. enables identification and analysis of trace amounts of DNA and RNA with greater sensitivity, accuracy and speed than conventional analysis. The...
Spectronics Corp.
UHV Windows
Custom fabricated sapphire viewports and sight windows for ultrahigh vacuum (UHV) systems and process machinery are available from Meller Optics Inc. The windows provide Moh 9 hardness and...
Meller Optics, Inc.
Tunable Laser
Designed with system integration in mind, a new tunable laser from Santec Corp. is suited for spectroscopy and optical coherence tomography (OCT). The HSL-1 is based on electrically pumped...
Santec Corp.
Biological Microscopes
Two new configurations of the FluoView FVMPE-RS series of multiphoton laser-scanning microscopes from Olympus can obtain vivid images 8 mm below the tissue surface, allowing observation of ultrafast...
Olympus Europa SE & Co. KG, Medical Systems & Micro-Imaging Solutions Group
Optomechanical Module
The IS-OGP by Siskiyou is an optomechanical module designed for integration of external laser beams into microscopes used for optogenetics experiments. It positions the focused laser...
Siskiyou Corporation
Laser Positioning Stages
New linear stages from Newport Corp. are engineered for extended operation in industrial environments with heavy duty cycles, like ultrafast laser micromachining, ablation, cutting or laser additive...
Newport Corporation

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