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BioPhotonics: December 2014

FEATURES
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Top Biophotonics Stories of 2014
QCL-based glucose testing, hyperspectral imaging and molecular techniques lead the list of the year’s most popular stories. The brain is having a big year. At the end of September, the...
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Global-Shutter vs. Rolling-Shutter Readouts
New sCMOS cameras overcome rolling-shutter artifacts by combining the best of both global and rolling shutters to achieve the simultaneous exposure with all rows, all while maintaining the frame rate...
Dr. Robert LaBelle, QImaging and Photometrics
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STED Microscopy Made Easy
Stimulated emission depletion microscopy surpasses diffraction-limited microscopy by offering much more information about structures. Combining STED with time-tagged data acquisition methods makes...
Olaf Schulz and Marcelle Koenig, Picoquant
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Collaboration Advances Intraoperative Assessment of Tumor Margins
Physicians, companies come together to address clinical translation issues. It’s a long-standing truth: For the biophotonics community to meet the needs and constraints of the medical...
Clémentine Bouyé, Tematys, and Carlos Lee, EPIC


EDITORIAL
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Celebrating Light and Life
Once again, we find ourselves on the threshold of a new year – and what a year it will be for the photonics industry and biophotonic technologies! The International Year of Light kicks off in January with festive opening ceremonies in Paris, but the calendar started filling some time ago. You can see the list of exciting events to be held around the world at the official website,...
Karen A. Newman, Group Publisher, karen.newman@photonics.com


BIOSCAN
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Doppler OCT Measures Cocaine’s Impact on Brain
A variant of optical coherence tomography has provided the first images of blood flow disruption in the brain caused by cocaine use. In a study involving mice repeatedly injected with cocaine over a 30-day period, researchers from Stony Brook University and the National Institutes of Health documented dramatic drops in blood flow speed, as well as microischemia, a precursor to a stroke. ...
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Raman Whispering Gallery Detects Nanoparticles
A Raman microlaser sensor can detect and count individual particles — including viruses — as small as 10 nm. Researchers led by Dr. Lan Yang of Washington University achieved...
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Optogenetics Swaps Memory Emotions
It may be possible to change negative memories into positive ones, and vice versa, using optogenetics techniques. A team at the Riken-MIT Center for Neural Circuit Genetics looked at how...
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SERS Advances Noninvasive Prostate Cancer Screening
Surface-enhanced Raman spectroscopy (SERS) could provide a noninvasive way to screen for prostate cancer. A team from Guangdong Medical College used SERS, as well as a spectral...
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Handheld Scanner Roots Out Brain Tumor Traces
A new Raman laser scanner could help surgeons more effectively remove cancerous brain tumors. A team from the Memorial Sloan Kettering Cancer Center is developing the new handheld device,...
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Chemical Treatment Makes 3-D Cell Cultures Clearer
A chemical treatment could lead to better imaging of cells in 3-D cultures. A team at Brown University made the finding while studying how neural tissues grow from stem cells. The...
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In Vivo Raman Technique Quickly Pinpoints Cholesterol
A new high-speed spectroscopy technique that can pinpoint where cells store cholesterol could be used to study obesity and diabetes. Researchers at Purdue University used...
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New Fluorescence Marker Enhances Bio-Imaging
A new line of red-shifted fluorescent tissue markers may enhance deep-tissue imaging. A team from the German Research Center for Environmental Health, in collaboration with the Max Planck...
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Fluorescence Technique Probes Muscular Dystrophy
Scientists are gaining new insight into muscular dystrophy using a form of high-resolution fluorescence microscopy. A team from the University of Southern California developed the technique,...
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Optogenetic Tool Guides Brain Mapping
A new optogenetics technique could help map neural networks in living organisms. Developed by a team at Caltech, the technique offers a clear view of the brain’s circuitry in action,...
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Interferometric Technique Targets Protein Shadows
A new optical method for targeting proteins could mean earlier diagnosis and more effective treatment for cancer. The technique makes individual proteins — including those...


RAPIDSCAN
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LightPath Caps ‘Year of Investment’
LightPath Technologies Inc. closed the books June 30 on fiscal 2014 with a net loss of $313,000 following what it called “a year of investment in our future.” The loss compared...
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Zeiss Reports Revenue Growth Despite Currency Effects
Carl Zeiss Meditec AG recently reported revenue of €673.7 million (about $878.8 million) in the first nine months of its fiscal year, an increase of 3.8 percent from the same period in the...
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OCT Poised To Expand Beyond Eye Care
Optical coherence tomography (OCT) will grow beyond ophthalmology applications into a €1 billion global market (about $1.29 billion) by 2019, the research group Tematys predicts. The...
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Zeiss, Janelia to Commercialize Fluorescence Technique
The Howard Hughes Medical Institute’s Janelia Research Campus has teamed up with Carl Zeiss Microscopy GmbH to commercialize Bessel beam plane illumination microscopy, also called lattice...
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National Energetics to Build 10 PW Research Laser
A consortium led by National Energetics Inc. has been awarded a contract over $40 million to develop and install a petawatt laser system at a research facility being built outside Prague. ...
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Industry Group Pledges $30M for Neuroimaging Research
Industry leaders plan to invest upwards of $30 million for photonics research and development in support of a White House neuroscience initiative. The National Photonics Initiative on...
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Phase Holographic Imaging Collaborates With Northeastern
A collaboration agreement between Phase Holographic Imaging (PHI) of Lund, Sweden, and Northeastern University of Boston has been announced. PHI will provide Northeastern with HoloMonitor...
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US Navy Enters Contract for Brain Scanner
Infrascan, a Philadelphia-based medical device firm specializing in brain injury diagnostic products, has entered into a four-year, $3.7 million contract with the U.S. Navy. The agreement...


POST SCRIPTS
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Taking Cues From The Sea
When man copies nature, it tends to be a smart move. Using nature’s design and strategy to solve human problems can allow us to bypass a lot of experimentation. One of the earliest instances of biomimicry may be Leonardo da Vinci’s sketches for a “flying machine” that mimics the wings of a bat. And architects have used the design of an egg – nature’s strongest,...


PRODUCTS
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Telepathology Workstation
The Pathscope 2 imaging and telepathology workstation from Spot Imaging Solutions can streamline routine slide examinations by annotating and archiving diagnostic fields of view to a laboratory...
SPOT Imaging Solutions
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Microscopy Software
New software from Olympus provides optical resolution up to 120 nm for the company’s FluoView FV1200 microscope. Olympus FV-OSR software enables confocal superresolution microscopy for...
Olympus Europa SE & Co. KG, Medical Systems & Micro-Imaging Solutions Group
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Photon Upconversion
The new Upcon upconverting nanoparticle system from Kaivogen Oy and Labrox Oy is designed to aid a number of low-background bioimaging applications. Upconverting nanoparticle labels (UCNPs)...
Labrox Oy
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Fiber Optic Sensors
New fiber optic signaling products are available from Micronor for use in harsh or hazardous industrial environments and medical applications. The MR382 series fiber optic U-beam sensor is a...
Micronor Inc.
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OCT Scanner
A new version of the VivoSight OCT multibeam optical coherence tomography scanner from Michelson Diagnostics incorporates a microcamera that provides a real-time, color, magnified view of the skin...
Michelson Diagnostics Ltd.
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Adjustable Fiber Collimators
Micro Laser Systems Inc. has introduced 2-µm adjustable fiber collimators for wavelengths from 1500 to 2300 nm. Users can tune to unique gas lines, such as CO2, HCl, CH4, H2O, NH3 or...
Micro Laser Systems, Inc.
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Pyroelectric Laser Sensor
A new fan-cooled pyroelectric laser sensor from Ophir Photonics covers wavelengths from 0.19 µm to 2.9 nm. The F-PE80BF-DIF-C is designed for high-power, short-pulse YAG lasers and...
Ophir - Spiricon LLC, Photonics
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Multicamera System
Photron has announced the FASTCAM Multi, a flexible, multihead camera system that permits high resolution, increased frame-rate performance and high-speed imaging in spaces too small for a...
Photron USA, Inc.
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4K Video Camera
With three chips and 8 MP, the UltraHD 4K video camera from Toshiba offers up to 1600 TV lines of resolution and switchable formats, from 4K at 50/59.94 Hz, to 1080p and 1080i. The UltraHD...
Toshiba Imaging Systems
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2-MP Camera
A new 2-MP camera from Point Grey Research Inc. is suited for applications in industrial inspection, 3-D imaging and bioscience. The Flea3 FL3-U3-20E4 uses a global shutter CMOS sensor...
Point Grey Research Inc.
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Microscopy Camera
The Excelis HD digital microscopy camera by Accu-Scope Inc. and Unitron Ltd. offers a 60-fps HDMI video preview and onboard image-capturing capabilities. It features live image output that...
ACCU-SCOPE Inc.
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DPSS Laser
The Lapa (Firefly) diode-pumped solid-state laser by RPMC Lasers Inc. offers up to 80 mJ of pulse energy at 1064 nm and pulse widths of 6 to 15 ns. It features a repetition rate of up to 30...
RPMC Lasers Inc.
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Fluorescence Illumination
The X-Cite 110-LED by Excelitas Technologies is a compact, white LED light source designed for fluorescence imaging applications. It provides excitation for DAPI, GFP, mCherry and Cy5...
Excelitas Technologies Corp.
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Modular Spectrograph
With intelligent, motorized adaptive focusing, the Shamrock 193i modular spectrograph from Andor Technology allows automated access to high spectral resolution in any grating, camera or wavelength...
Andor Technology plc, Corporate Headquarters
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Surface Profiling
Craic Technologies has announced Spectral Surface Mapping (S2M) capabilities for its UV-VIS-NIR microspectrophotometers. With microscopic spatial resolution, surface profiles can be created...
CRAIC Technologies
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Software for FLIM, FCS
A software upgrade kit from PicoQuant and Nikon offers a new interface between PicoQuant’s SymPhoTime 64 and Nikon’s NIS-Elements imaging software, and can be adapted to all Nikon...
PicoQuant GmbH

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