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BioPhotonics: February 2014

FEATURES
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Simplified Approach Makes Two-Photon Multicolor Imaging Less Costly
A fixed-wavelength laser in combination with a nondescanned hyperspectral detection system obtains clean images when used with triple-stained samples with all dyes excited simultaneously. ...
Tilman Franke,1 Jose L. Serrano-Velez,2,3 Nydia L. Rivera-Rivera,2,3 Eduardo Rosa-Molinarz,3 and atthias Langhorst1
1FEI Munich (Formerly Till Photonics, 2University of Puerto Rico-Rio Piedras, 3University of Puerto Rico-Medical Sciences
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SERS on the Verge of Diagnostic Success
Surface-enhanced Raman spectroscopy is the emerging star of Raman spectroscopy, promising the ultimate in sensitivity, early disease diagnosis and more. After years of exclusion as an academic...
Marie Freebody, Contributing Editor, marie.freebody@photonics.com
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Raman Technique Offers Promise for Clinical Applications
Intraoperative imaging of brain tumors is among the potential uses that could benefit from Raman imaging. Raman imaging has been explored for a range of uses; among the most exciting of these...
Gary Boas, News Editor, gary.boas@photonics.com
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Fast Camera Tracks Agile Survival Artists
Biologists use high-speed imaging to study how microorganisms move. Some like it hot – for example, micro-organisms that live in the deep sea on “black smokers,” where heat...
Dr. Gerhard Holst, PCO AG


EDITORIAL
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Winning Innovation
It is late January as I write this, and we are just days away from announcing the winners of the 2014 Prism Awards for Photonics Innovation, including awards directly related to biophotonics. The Prism Awards are presented jointly by SPIE and Photonics Media at an event held annually during Photonics West. By the time you receive this issue, the winners will be posted at the official Prism Awards...
Karen A. Newman, Group Publisher, karen.newman@photonics.com


BIOSCAN
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Multispectral Camera Detects Tumors During Surgery
A multispectral camera that simultaneously displays several fluorescent dyes and the reflectance image in real time could help surgeons ensure that they don't leave behind tiny pieces of malignant tumors. Obviously, cancer patients have a better chance of recovering if their tumors are completely removed. But tiny clusters often are difficult for surgeons to recognize and remove, and the...
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Nanorods Synthesized for Large-Scale Manufacturing
A new technique that produces nanoscale gold rods in large quantities while also controlling their optical properties and dimensions could facilitate their high-volume manufacture for applications in...
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Compact Laser Generates Research-Quality X-rays
A novel method generates research-quality x-rays using a "tabletop" laser, making such light sources more practical for advanced research. High-quality x-rays — needed for applications...
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Laser Reveals Photosynthetic Processes
Scientists have used an ultrafast laser to study a photosynthetic complex — arguably the most important bit of organic chemistry on the planet — in its complete functioning state. ...
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Lasers deemed highly effective for excessive scarring
Laser therapy approaches are effective for treating excessive scarring resulting from abnormal wound healing, but not all scars are affected equally, according to a recent review article. Dr....
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Phone camera becomes mini-microscope for diagnostics
Microscopy is relatively easy to perform and at low cost, which makes it a universal diagnostic method for most globally important parasitic infections. But many methods are limited to well-equipped...
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Molecular probe detects early signs of MS
A new fluorescence-based molecular probe can detect multiple sclerosis (MS) at its earliest stage – even before the onset of physical signs. MS develops when the body’s immune...


RAPIDSCAN
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First Horizon 2020 Photonics Projects Open
The European Commission presented on Wednesday its first calls for projects under the Horizon 2020 program, the European Union's seven-year, €80 billion research and innovation program. Those calls include €47 million specifically earmarked for photonics-related proposals. Horizon 2020 will be worth more than €15 billion over its first two years, and the funding is...
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Georgia State Creates Nano-Optics Center
Georgia State University announced last week that it has created a research center to focus on developing nanotechnology tools and instruments, The Center for Nano-Optics. “Creation of...
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EPIC Celebrates 10 Years
EPIC, the European Photonics Industry Consortium, marked its 10th anniversary last week with a number of activities involving the European photonics community, including meetings with the European...
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NIH funds optogenetics research at UT Arlington
Optogenetics research to fight the sight-deteriorating disease retinitis pigmentosa has received more than $384,269 from the National Institutes of Health (NIH). Dr. Samarendra Mohanty, assistant...
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Market for home health sensors set to explode
The market for sensors in home health care applications will explode from $559 million in 2013 to $1.2 billion by 2018, according to a recent report from Research and Markets. The aging global...


POST SCRIPTS
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Smile and say ‘Microinvertebrates!’
Photographers know that good photos of children and pets can involve certain forms of coaxing: For children, you tell them to say “Cheese!” because it will look like they’re smiling; for pets, you bribe them with tasty treats to pose for a sweet second or two. Dr. Igor Siwanowicz’s subject required a very special kind of treat: single-celled organisms. But the bribe...
Laura Marshall, Managing Editor, laura.marshall@photonics.com


PRODUCTS
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MESA 50 X-Ray Fluorescence Analyzer
The MESA 50 energy-dispersive x-ray fluorescence analyzer from Horiba Scientific screens samples containing hazardous elements such as lead, cadmium, chromium, mercury and bromine for RoHS...
HORIBA Scientific, HORIBA Scientific
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Tecnai Femto Ultrafast Electron Microscope
The Tecnai Femto ultrafast electron microscope from FEI Co. captures ultrafast events and processes measured in femtoseconds, including the absorption of light energy and its transformation into...
FEI Life Sciences
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IK-HR3H HD Video Camera
Toshiba Imaging has released the IK-HR3H, the second in its series of HD remote-head cameras. The one-chip CMOS, 2.1-MP video camera provides color accuracy and advanced noise reduction...
Toshiba Imaging Systems
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MPA Info+ Multiphoton-Absorber Database
The MPA Info+ by Simphotek is a searchable database of multiphoton absorbers for applications such as biomedical imaging, lithography, 3-D optical storage, stimulated emission depletion microscopy,...
Simphotek Inc.
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Holospec Multitrack Imaging Spectrograph
The Holospec multitrack imaging spectrograph by Andor Technology is suitable for various applications including weak nanostructure photoluminescence; micro-Raman mapping, including tip-enhanced Raman...
Andor Technology plc, Corporate Headquarters
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Dual-Inverted Selective Plane Illumination Microscopy
Applied Scientific Instrumentation (ASI) Inc.’s dual-inverted selective plane illumination microscope generates 3-D volumes with isotropic resolution (330 nm) in all directions. Axial...
Applied Scientific Instrumentation, Inc.
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A1 MP+, A1R MP+ Multiphoton Confocal Imaging
Nikon Inc. has added three upgrades to its multiphoton confocal microscopy systems, A1 MP+ and A1R MP+, to enable deep-tissue two-photon fluorescence imaging at longer wavelengths. The...
Nikon Instruments Inc.
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Nunavut Linear Array Camera Enhancements
BaySpec Inc. has added new wavelength ranges to its line of Nunavut deep-cooled linear array cameras, improved the low-noise electronics and provided optional water cooling down to –100 °C....
BaySpec, Inc.
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RFG92 Monolithic Fiber Optic Faceplates
Schott has added RFG92 monolithic fiber optic faceplates to its medical technology line for use in digital x-ray sensors employing CMOS technology. Manufactured according to customer...
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Elyra P.1 3-D Superresolution Microscopy
Zeiss has added the Elyra P.1 module to its 3-D microscopy portfolio. The system enables superresolution photoactivated localization microscopy (PALM) for endogenously expressed photoswitchable...
Carl Zeiss Microscopy GmbH, Optical Sensor Systems
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Spark-1300 OCT System
Wasatch Photonics Inc. has announced the Spark-1300 OCT system for material inspection and medical diagnostics, including cardiovascular and dermatological research. The spectral-domain...
Wasatch Photonics, Inc.
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PDT Research Illumination Kit
Modulight Inc. is offering a photodynamic therapy (PDT) illumination kit for R&D applications. PDT is a type of treatment for cancer, bacterial infections and inflammation that is based on...
Modulight, Inc.
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TechSpec Bandpass Filters
New TechSpec hard-coated OD4 25-nm bandpass filters from Edmund Optics are suitable for life science instrumentation and single-photon microscopy applications. The filters offer high...
Edmund Optics, Inc.
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Xineos-1515 CMOS X-Ray Detector
Teledyne Dalsa Inc. has added the Xineos-1515 CMOS x-ray detector to its flat detector series for clinical fixed and mobile applications such as C-arms, fluoroscopy and 3-D orthopedic imaging...
Teledyne DALSA, Machine Vision OEM Components
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Compact-506 Optical Scanner
The Compact-506 galvanometer-based optical scanner from ScannerMax is suitable for use in compact medical devices and laser image projection. Its strong rotor construction and 6-mm bearings...
ScannerMAX
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Skyscan 1272 Micro-CT System
Micro Photonics Inc. is offering the SkyScan 1272, a benchtop x-ray micro-CT (computed tomography) system from Bruker MicroCT that can nondestructively visualize more than 200-MP virtual slices...
Micro Photonics, Inc.
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eosens TS3 Cameras
The eosens TS3 high-speed cameras from Mikrotron GmbH are suitable for applications in industry, R&D, medicine, biology, sport and science. The cameras capture up to 500 fps at 1280...
Mikrotron GmbH
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GL SPECTIS 5.0 Touch Spectrophotometer
Saelig Co. Inc. has introduced GL Optic’s GL SPECTIS 5.0 Touch, a portable spectrophotometer that obtains light-measurement data ranging from the NIR to the UV with laboratory accuracy. ...
Saelig Co. Inc.
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STS-UV Microspectrometer
The STS-UV microspectrometer from Ocean Optics Inc. is suitable for integration into spectroscopy instrumentation, medical devices, process monitoring and other applications. The device...
Ocean Optics, Inc.
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NFM SWIR Fluorescence Microscope
The NFM microscope from Applied NanoFluorescence images individual single-walled carbon nanotubes (SWCNTs) through their intrinsic short-wave IR fluorescence. The system is suitable for research...
Applied NanoFluorescence, LLC
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SpectraMax MiniMax 300 Imaging Cytometer
The SpectraMax MiniMax 300 fluorescence imaging cytometer from Molecular Devices provides cellular visualization and cell-based analysis for a range of cell-counting and cell-confluency measurement...
Molecular Devices, LLC
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Cytation 3 Cell Imager
BioTek Instruments Inc. has added new features to its Cytation 3 cell-imaging multimode reader. The instrument combines digital microscopy and conventional microplate detection to provide cellular...

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