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BioPhotonics: November 2009

FEATURES
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Label-Free Live-Cell Imaging for High-Content Screening
High-content screening is the collection of multiple data parameters in parallel from the same cellular samples. It has evolved into a mature technique typically using automated fluorescence...
David L. Drapcho and Kris Ver Donck, Digilab Inc., with Terry McCann, TJM Consultancy
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CMOS X-Ray Cameras for High-Resolution 3-D Brain Activity Research
Over the past four decades, neurophysiologists have studied brain structures and activity using extracellular microelectrodes to characterize the response of neurons in vivo. But there are still many...
Alana Achterkirchen, Rad-icon Imaging
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Clinical microscopy’s changing view
For clinical microscopy, the familiar view is changing, as images once seen through eyepieces are increasingly viewed on a screen. The result could be greater collaboration in the operating room,...
Hank Hogan, Contributing Editor, hank@hankhogan.com
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Medical Device Companies Try Peering into the Future
The past year has not been as gloomy for the medical device industry as it has, say, for home builders, automakers and just about everyone else. In the US, demand for the latest and greatest...
Lynn Savage, Features Editor, lynn.savage@laurin.com


EDITORIAL
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Research for the sake of research
The importance of basic science research was highlighted last month when the Nobel Assembly at Karolinska Institutet in Stockholm, Sweden, announced that the 2009 Nobel Prize in physiology or...
Tom Laurin
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Change the review rules
I appreciated Gary Boas’ examination of the changes in the National Institutes of Health’s peer review process for extramural grant applications (“Who Reviews the Review?,”...


POST SCRIPTS
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Ready for my close-up!
The curtain has closed on another Small World photomicrography contest, which has been hosted annually by Nikon since the mid-1970s. Every year, amateur and professional researchers, photographers and microscopists from around the globe put forth their best images to be judged. Nikon announced the winners on Oct. 8. Dennis Breitsprecher of Hannover Medical School in Germany took this picture...
Lynn Savage, lynn.savage@laurin.com


BREAKTHROUGHMEDIA
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Laboratory Accreditation
Available from ASTM International, the online compilation ASTM Standards for Laboratory Accreditation and Personnel Certification provides access to 12 ASTM and three ANSI/ISO/IEC standards on laboratory and inspection agency accreditation. The globally recognized standards cover areas such as analysis and interpretation of proficiency test program results, and evaluation of agencies involved in...
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3-D X-Ray Imaging
Xradia Inc., a manufacturer of high-resolution 3-D x-ray imaging systems, has launched a Web site that includes a gallery of 3-D images and movies for its major application markets: nanotechnology,...
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Microscopy Stages
Temperature-controlled microscopy specialist Linkam Scientific Instruments Ltd. offers a redesigned Web site to facilitate access to information on its heating and freezing stages, which enable...
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Multilingual Access
BioTek Instruments Inc., a supplier of microplate instrumentation technology, has launched Web sites in Spanish, French, German, Chinese and Japanese for its international customers. The sites,...
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Image-Guided Therapy
Part of the “Engineering in Medicine & Biology” series, the 458-page volume Image-Guided Therapy Systems provides coverage on topics such as neurosurgery, MRI-guided and robotic surgery, OCT,...
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Webcast Library
PerkinElmer Inc. has released its Application Webcast Library DVD. The webcasts feature industry experts who discuss and demonstrate application-specific solutions in areas such as forensics,...
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Research Articles
The Optical Society of America has launched the interactive Web page “Spotlight on Optics,” which will provide summaries of select research articles from all 13 of its journals on a regular basis....
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Adrenal Imaging
Part of the “Contemporary Medical Imaging” series, the 234-page book Adrenal Imaging highlights developments in the field and reviews established adrenal imaging findings, algorithms and techniques...
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SEM Basics
JEOL Ltd. has released a 31-page publication titled SEM: Scanning Electron Microscope A to Z: Basic Knowledge for Using the SEM. Available for download on the JEOL USA Web site, the booklet covers...
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Biotech Optics
Edmund Optics has released its Precision Biotech Optics catalog, which features in-stock products for researchers and developers in fields ranging from DNA sequencing to microscopy to biomedicine. It...
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Photomedicine
The Mary Ann Liebert Companies has made available online all published issues of the journal Photomedicine and Laser Surgery back to Vol. 1, No. 1, in 1983. The compilation, which includes 1900...


PRODUCTS
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ICCD Camera
Princeton Instruments has released the PI-Max 3, an intensified CCD (ICCD) camera for time-resolved imaging and spectroscopy applications. It offers readout ranging from video rates to thousands of frames per second. Delivering a sustained gating repetition rate of 1 MHz, it has a built-in timing generator that can store a sequence of gate delays and widths to generate time vs. intensity data. It...
Princeton Instruments
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Laser Bars
A conduction-cooled, visible diode laser bar series has been introduced by Dilas Diode Laser Inc. Available in 632-, 635-, 638-, 650- and 677-nm wavelengths with optical CW output power between 4 and...
DILAS Diode Laser, Inc.
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Diode Laser
Toptica Photonics has announced the iBeam smart, a compact diode laser for applications such as flow cytometry, confocal microscopy, microlithography, retina scanning and microplate readout. The...
TOPTICA Photonics AG
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USB Microscope
The ProScope HR2 handheld USB microscope from Bodelin Technologies Inc. with the custom Aptina imager is suitable for applications such as telemedicine, manufacturing quality control and law...
Bodelin Technologies
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UV Cross-Linker
Spectronics Corp. has released the Select XLE-Series UV cross-linker that covalently binds nucleic acids to membranes in <30 s. It allows users to identify and analyze trace amounts of DNA and RNA...
Spectronics Corp.
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3-D Surface Profiler
Nikon Instruments Inc. has unveiled the BW-H501 high-speed 3-D surface profile system for rapid inspection of object surface roughness. It features real-time height observation and measurement with...
Nikon Instruments Inc.
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Green Laser
Coherent Inc. has introduced the Matrix 532-8-100 Q-switched, diode-pumped, solid-state laser for high-throughput micromachining tasks in solar, semiconductor and medical device manufacturing. The...
Coherent Inc.
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Smart Camera
Dalsa Corp. has released its BOA machine vision system for industrial applications. The highly integrated smart camera incorporates multiple processing engines and offers embedded application...
Teledyne DALSA, Machine Vision OEM Components
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Secondary Antibodies
Li-Cor Biosciences has unveiled goat anti-mouse and goat anti-rabbit secondary antibodies labeled with horseradish peroxidase. They are optimized for use with Chemi-IR detection kits, as well as with...
LI-COR Biosciences, Biotechnology
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Slide Scanner
Leica Microsystems GmbH has announced the SCN400 slide scanner as an alternative to the microscope for examining histological samples. The custom-tailored lens for a digital sensor ensures that the...
Leica Microsystems GmbH
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Biomarker Assay
Invitrogen, part of Life Technologies Corp., has made available the PlexMark 3 Renal Biomarker Panel Assay as a noninvasive research tool for performing post-transplant kidney function studies. It...
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Tuberculosis Detector
Applied Spectral Imaging has released the TB-Finder, computer-aided technology for detecting signs of tuberculosis in tissue or sputum. Designed especially for allocating acid-fast tuberculosis...
Applied Spectral Imaging, Inc.
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Polarization Camera
The FD-1665P, a compact three-CCD real-time polarization camera, has been introduced by FluxData Inc. for use in medical, surveillance, defense and machine vision applications. Based on the company’s...
FluxData, Inc.
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Slide Scanner
The NanoZoomer 2.0 series slide scanners from Hamamatsu Corp. can convert a 20 × 20-mm area on a glass slide into a 1.9-gigapixel color image in less than 2 min. The virtual slides can be...
Hamamatsu Corporation
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Clinical Microscope
Olympus Life Science Europa GmbH has unveiled the CX21LED clinical microscope with built-in LED illumination. Suitable for biological and medical applications, the imaging system can illuminate...
Olympus Europa SE & Co. KG, Medical Systems & Micro-Imaging Solutions Group
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Picosecond Laser
Lumera Laser has announced an increase in the average power of its picosecond laser family. The Rapid lasers have applications in semiconductor, electronics, solar cell, medical and microfluidics...
Coherent Kaiserslautern GmbH
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Compact Green Laser
Laser Operations LLC has released the BrightLock Ultra-GT, a compact and passively cooled green laser based on proprietary QPC Lasers monolithic chip wavelength stabilization technology. The platform...
Laser Operations LLC, QPC Lasers
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Digital Holography Microscope
Lyncée Tec SA has introduced a new digital holography microscope series for real-time 3-D topography with nanometer resolution. The DHM R2000 features two wavelengths working simultaneously for...
Lyncee Tec SA
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Microscopy Camera
To replace its Retiga EXi, QImaging has unveiled the EXi Aqua bioimaging microscopy camera. The 20-MHz, 14-bit camera features low read noise, high sensitivity, active cooling, low dark current,...
QImaging
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Digital Radiography
Rad-icon Imaging Corp. has extended its product line of very large area digital CMOS x-ray cameras with the SkiaGraph10 EV. With a total active sensing area of 8 × 10 in., it delivers real-time...
Teledyne Rad-icon Imaging
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Two-Gas Mixer
Warner Instrument Corp. has released the 2GF two-gas mixer to generate CO2/air mixtures with adjustable concentrations of CO2 in the range of 0 to 15%. Compatible with all microscope stage...
Warner Instruments, LLC
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Bone Density Software
Software for image analysis of bone density is now available from Carestream Molecular Imaging, a division of Carestream Health Inc. Its cylindrical model facilitates bone density analysis of small...
Carestream Health, Molecular Imaging
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Single-Photon Detection
For its id201 single-photon-detection module at near-infrared wavelengths, id Quantique SA has announced a reduced noise level. The hermetically sealed diode, suitable for use in ambient light,...
ID Quantique
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NIR Spectrometer
B&W Tek Inc. has introduced the Sol 2.5 InGaAs array NIR spectrometer. Covering the 1700- to 2500-nm spectral range, it offers four sensitivity and dynamic range settings, 9-nm FWHM resolution...
B&W Tek, Inc.
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Cartesian Geometry Spectrometer
The Rigaku NEX CG is a benchtop energy-dispersive x-ray fluorescence spectrometer for nondestructive qualitative and quantitative analysis of major and minor atomic elements in solids, liquids,...
Rigaku Americas Corp.
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Laminar Flow Workstations
Jeio Tech Inc. has launched a line of Class 4 laminar flow clean benches. The workstations feature 304 stainless steel work surfaces, a polyester pre-filter and an ergonomic 5° sloped front. They are...
Jeio Tech Co., Ltd.
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Fluorescent Protein Flashlight
The NightSea DFP-1 dual fluorescent protein flashlight from NightSea can be used in transgenic experiments to screen for both green and red fluorescent proteins. It includes two high-intensity LEDs,...
NIGHTSEA

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