TriMScope from LaVision BioTec GmbH, a state-of-the-art multifocal, multiphoton microscope, is based on a patented beamsplitter that can divide an incoming laser beam into 64 beamlets and scan them simultaneously in the object plane. The company says the result is images that are 64 times brighter or rates that are 64 times higher than those produced by single-beam two-photon scanning microscopes. The foci in the object plane are aligned in a single line, and their number can be switched from 64 to 32, 16, 8, 4 and a single beam. The device operates between 750 and 1150 nm and is suitable for real-time 3-D microscopy applications such as kinetics imaging on living cells, cell compartment motion, optical tweezers, observation of neurophysiological processes and picosecond time-resolved microscopy. Image rates up to 3.5 kHz are possible, and optical throughput is >90%.