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  • Chameleon Ultra
Nov 2005
Coherent Inc.Request Info
Laser Extends MPE Microscopy Capabilities
SANTA CLARA, Calif., Nov. 8 -- Laser maker Coherent Inc.'s new Chameleon Ultra laser extends the capabilities of multiphoton excitation (MPE) microscopy by delivering an unmatched combination of wavelength tuning range, fast scanning and high peak power, according to the company. This new ultrafast laser tunes from 690 to 1040 nm, enabling calcium uncaging, autofluorescence techniques and the use of green, blue and cyan fluorescent proteins, as well as deeper imaging within samples. A fast scanning speed of 25 nm/s further supports calcium uncaging and facilitates multicolor imaging. The Chameleon Ultra also offers high peak power (>2 W at 800 nm) throughout its tuning range for a stronger MPE signal.

The Chameleon Ultra output has an M2 <1.1 and a round beam (ellipticity between 0.9 and 1.1) for optimum coupling with the microscope optical system. Chameleon Ultra also requires no manual adjustments, and is operated via a simple push-button, menu-driven interface on the power supply’s front panel. The laser can be controlled by a host computer using the supplied graphical user interface or, alternatively, the user can develop custom firmware based on the RS-232 command set or Labview VI.

For more information, visit:; e-mail:

Coherent Inc.
5100 Patrick Henry Dr.
Santa Clara, CA 95054
Phone: (408) 764-4000
Fax: (408) 764-4800
Sales: (800) 527-3786


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An instrument consisting essentially of a tube 160 mm long, with an objective lens at the distant end and an eyepiece at the near end. The objective forms a real aerial image of the object in the focal plane of the eyepiece where it is observed by the eye. The overall magnifying power is equal to the linear magnification of the objective multiplied by the magnifying power of the eyepiece. The eyepiece can be replaced by a film to photograph the primary image, or a positive or negative relay...
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