Carl Zeiss MicroImaging Inc. has combined its LSM 510 Meta and LSM 5 Live confocal laser scanning microscopes to create a multipurpose workstation called the LSM 5 Duo. Features include fast line scanning, ultraprecise point scanning, spectral and nonlinear imaging, and flexible optical sample micromanipulation. All of the system functions are controlled by the same software and real-time electronics and share the same lasers and microscope. Ultrafast acquisition capabilities enable observation of dynamic processes up to the kilohertz range. The AchroGate beamsplitter and high-quantum-efficiency CCD line detection combination produces high sensitivity. Acquisition in multiple Meta channels enables spectral imaging.