Request InfoLeica Microsystems GmbHThe Fluo LED4000 and Fluo LED100 fluorescence microscopy illumination systems from Leica Microsystems GmbH are suitable for cell biology applications. The 4000 model offers users five freely combinable LED modules and specific excitation of fluorochromes with one wavelength. The company says that its stable excitation intensities yield better quantification and that its reduced stray light produces higher-contrast images. Most suitable for applications requiring one fluorochrome only, the 100 model delivers excitation at 470 nm. It is compatible with all microscopes equipped for fluorescence...See full productRelated content from Photonics MediaPRODUCTSPromoted Content June 2023 IssueNanopositioning for High-Res MicroscopyPI's new Fast Focus Stages and Multi-Axis Piezo Flexure Scanners for Microscopy are designed to improve the performance of high-resolution microscopy. Choice of piezo and voice coil motors....Photonics.com 2/8/2024Fluorescence Imaging LensesThe Melles Griot XPLAN™ CCG Lens Series from IDEX Health & Science are fluorescence microscope imaging lenses for life science and medical applications. The lenses use a larger field of...BioPhotonics Nov/Dec 2022 IssueHolotomography MicroscopeThe HT-X1 high-resolution holotomography microscope from Tomocube Inc. features an incoherent light source and is suited for higher-throughput and automated screening applications. The device...BioPhotonics Jul/Aug 2023 IssueMicroscopy SoftwareVersion 4.1 of the SLIDEVIEW™ VS200 microscopy software from Olympus Corp. and Evident Scientific adds an optical sectioning device for high-contrast, blur-free imaging. The SILA optical...ARTICLESBioPhotonics Sep/Oct 2022 IssueA Multiphoton Microscope Enables Portable 3D Biological ImagingFor decades, optical microscopy has provided the mechanism with which to image cells and tissue for the purposes of cancer research, digital pathology, and the study of the brain. Samples are...BioPhotonics Jul/Aug 2022 IssueLaser Endomicroscopy Enables Real-time Detection of Lung CancerResearchers at the Abramson Cancer Center at the University of Pennsylvania have developed a method to detect lung cancer at the cellular level in real time during biopsy. The method ensures earlier...BioPhotonics Jan/Feb 2024 IssueCenter for Photonics in Infection Research to Open in JenaGermany’s Federal Ministry of Education and Research is funding the establishment of the Leibniz Centre for Photonics in Infection Research (LPI) at the Jena University Hospital. The center...BioPhotonics Mar/Apr 2024 IssueAI-aided Implant Captures Deep Brain ImagesA neural implant developed at the University of California San Diego could help advance the path to minimally invasive brain-computer interface (BCI) technology. The implant provides high-resolution...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookLasers for Microscopy: Major TrendsLaser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...Photonics HandbookMicroscopy Illumination: Considering Nonlaser Light SourcesAs recently as five years ago, shopping for a microscope light source was fairly straightforward. For routine applications, it was tungsten halogen, typically 100 W, while for fluorescence, it was an...Photonics HandbookInterferometry: Measuring with LightAn interferometer is an instrument that compares the position or surface structure of two objects. The basic two-beam division of amplitude interferometer components consists of a light source, a...Photonics HandbookNanopositioning: A Step AheadBy its original definition, a nanopositioning device is a mechanism capable of repeatedly delivering motion in increments as small as one nanometer. Lately demands from industry and research have...WHITEPAPERSPhotonics.com 12/8/2022Sub 50 Femtosecond Pulse Lasers for Gentler Multiphoton MicroscopyFinding the ideal ultra-fast laser source for a multiphoton imaging setup is not trivial. It is a fine balance between peak power, pulse energy and laser wavelength. In this white paper we show that...Photonics.com 4/20/2023Is a DIY Microscope for You?For some advanced microscopy and nanoscopy techniques it becomes necessary to modify existing instrumentation or build an instrument from scratch. This article helps readers determine whether a...Photonics.com 2/21/2024Dual Inverted Selective Plane Illumination MicroscopeAn overview of diSPIMPhotonics.com 10/19/2023Clean, New Bioenergy Sources: One Molecule at a TimeResearchers at Penn State University are spearheading a multidisciplinary research effort to explore ways to produce bioethanol more efficiently from lignocellulose. Importantly, this is not corn...WEBINARSPhotonics.com 10/28/2021Multimodal Imaging: Photoacoustic Imaging and MoreTransenergy imaging modalities have been significantly explored to overcome existing problems in conventional imaging modalities with respect to spatial/temporal resolutions, penetration depth,...Photonics.com 10/27/2022KEYNOTE: Specialized Laser Probes Capture Fluorescence Detail and Drive DiagnosticsArrigoni discusses the various applications of lasers to biology and medicine, and categorizes them by the type of process involved and the most significant trends: Fluorescence (spectral) imaging by...Photonics.com 10/26/2021Reshaping Histopathology with Deep LearningRecent advancements in deep learning have enabled a new state of the art for results in microscopy. Yair Rivenson focuses on deep-learning-powered image enhancement tasks and, specifically, on the...Photonics.com 12/8/2022Low-Cost Compact Optical Spectroscopy and Novel Spectroscopic AlgorithmsReal-time monitoring of nanoparticle delivery within biological models is essential for the optimization of nanoparticle-mediated therapies, but few techniques exist to conveniently monitor...PHOTONICS DICTIONARY+ TERMSPhotonics DictionarysupercontinuumSupercontinuum refers to a broad spectrum of light that spans a wide range of wavelengths, typically from the visible to the near-infrared or even mid-infrared regions of the electromagnetic...Photonics Dictionarylateral shearing interferometerA lateral shearing interferometer is an optical device used in interferometry to measure phase differences between two beams of light. Interferometry is a technique that combines and analyzes...Photonics Dictionaryphase-contrast generationMicroscopy technique to convert the phase structure of the wave transmitted or reflected by the specimen into a corresponding intensity structure in the image plane.Photonics Dictionarylight sheet fluorescence microscopyAlso known as single plane illumination microscopy (SPIM), this process was designed for imaging of sensitive samples and fast biological processes in vivo. In this method, a light sheet illuminates...VIDEOSPhotonics.com 10/12/2021pco - Frequency Domain Fluorescence Lifetime Imaging Microscopy - A Hands-On SessionThis hands-on session about FD-FLIM by Gerhard Holst from PCO AG was given as part of the FLIM Symposium "Beginners Guide to Fluorescence Lifetime Imaging in Life Sciences".Photonics.com 11/20/2023New ZL41 Cell & Sona sCMOS - Easy, Flexible, Cost-Effective Super Resolution Microscopy - Andor TechnologyEasy and Cost-Effective Super-Resolution to ~100 nm. Andor has introduced two new highly innovative sCMOS cameras, both delivering easy and cost-effective access to super-resolution capabilities and...Photonics.com 5/2/2022Applied Scientific InstrumentationEstablished in 1990, Applied Scientific Instrumentation is a reknown American company committed to the advancement of science. ASI products have been thoroughly tested and evaluated in numerous labs...Photonics.com 11/20/2023New Dragonfly 600 Confocal Microscope System - Andor TechnologyThe Dragonfly 600 confocal microscope system delivers outstanding multi-dimensional images from subcellular (nm) to whole organism (cm), while significantly boosting productivity. Its unrivalled...PHOTONICS BUYERS' GUIDE CATEGORIESPicosecond LasersMedical/Biomedical Light SourcesSupercontinuum LasersMicropositionersCOMPANIESPhotonics Buyers' GuideOZ Optics LimitedEstablished in 1985, OZ Optics is a leading worldwide supplier of fiber optic components, test equipment and sensors. OZ Optics manufactures its products in three locations, Ottawa (Canada),...Photonics Buyers' GuideAndor TechnologyAndor Technology Ltd is a global developer and manufacturer of high-performance scientific cameras, microscopy systems and spectrographs for academic, government, and industrial applications. Founded...Photonics Buyers' GuideOptikos CorporationThe Optical Engineering Experts® Optikos designs and manufactures metrology products for measuring and assuring optical image quality; and provides optical engineering design, development,...Photonics Buyers' GuideCASTECH INC.CASTECH is a recognized leading supplier of nonlinear optical crystals, laser crystals and precision optical components for laser, telecom, medical, analysis and detector markets. Products...