Request InfoCoolLED Ltd.CoolLED has introduced the pE-2 collimator for its four-wavelength precisExcite system. It offers independent control for each fluorophore when exciting cyan fluorescent protein and yellow fluorescent protein or GFP and mCherry (or dsRed). It does not require the use of an excitation filter wheel, and it can achieve solid-state switching of excitation wavelengths in microseconds.See full productRelated content from Photonics MediaPRODUCTSBioPhotonics Mar/Apr 2023 IssueLED Illumination SystemsThe pE-400 series of four-wavelength LED illumination systems from CoolLED provide sophisticated control and powerful illumination for cost-effective fluorescence microscopy. The series...BioPhotonics May/Jun 2023 IssueFemtosecond LaserThe Jasper Micro compact femtosecond laser from Fluence Technology is air-cooled and compact for integration in limited space. Pulse duration is tunable from <270 fs to 8 ps, and optionally...Promoted Content September 2022 IssueWe Make Your Laser for Medical ApplicationsThe FISBA READYBeam™ is our answer to customers' increasing demand for a compact, powerful, and reliable multicolor laser source that can be easily integrated into existing set-ups. The...Vision Spectra Summer 2023 IssueArea Scan CameraThe EoSens 10CCX12-FM 10 MP area scan camera from Mikrotron GmbH features a global shutter for demanding vision applications in industrial inspection, life science imaging, and 4K video applications...ARTICLESBioPhotonics Jan/Feb 2023 IssueFluorophore Modified to Expand Monitoring of Cell DynamicsA genetically modified fluorescent protein has exhibited the shortest fluorescence emission wavelength to date, researchers at Osaka University reported. 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The new USMAG (United States Military, Aerospace, and Government) Alliance aims to bring together a...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookFluorescence Lifetime Imaging: Choosing the Best ApproachThe term fluorescence is often applied as a synonym for photoluminescence, although luminescence actually covers fluorescence and phosphorescence. Both of these terms describe the process of...Photonics HandbookLight-Emitting Diodes: A PrimerThe wavelength range of commercially available LEDs with single-element output power of at least 5 mW is 275 to 950 nm. Each wavelength range is made from a specific semiconductor material family,...Photonics HandbookAspheric Lenses: Design ConsiderationsAspheric surfaces are powerful tools that combine the optical corrections of multiple lenses into a single element (Figure 1) and affect performance in ways that spherical optics cannot. 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Extra virgin, virgin, and lower-quality olive oils can be distinguished by...Photonics.com 9/12/2022Ingenuity + Instrumentation: Creating a Novel 4D Microscopy MethodTracking particles at the micro or nanoscale is inherently difficult due to the complexity of the systems studied, as well as the technical challenges: a blend of instrument design, photonics,...Photonics.com 10/19/2023Clean, New Bioenergy Sources: One Molecule at a TimeResearchers at Penn State University are spearheading a multidisciplinary research effort to explore ways to produce bioethanol more efficiently from lignocellulose. Importantly, this is not corn...Photonics.com 5/24/2022Medical Optics from Shanghai OpticsProducing optics for medical devices has its own unique set of difficulties and challenges including cost, turnaround time, performance, and standards. This paper talks about those challenges and...WEBINARSPhotonics.com 6/17/2021Multi-Line Lasers or Laser Combiners: What Solution Is Best for Fluorescence Imaging?Fluorescence imaging is a key technique in both biomedical research and clinical diagnosis. Fluorescence-based microscopy for high-resolution and high-throughput multifluorophore imaging typically...Photonics.com 6/2/2022Advances in LED Illumination for Fluorescence ImagingLED illumination for fluorescence microscopy systems has progressed significantly from a time when LED sources had low optical power and a limited range of wavelengths. While the benefits of LED...Photonics.com 10/27/2021Expanding Capabilities with Optimized NIR Confocal ImagingFluorescence microscopy historically has been dominated by blue, green, and red imaging. Although this limitation is acceptable for some applications, multiplexing and deep tissue imaging suffer with...Photonics.com 10/27/2022Multiline Lasers Help Simplify Systems Based on Light-Sheet Microscopy for Clinical ApplicationsFluorescence imaging using lasers is a key technique in both biomedical research and clinical applications. Fluorescence-based microscopy for high-resolution and high-throughput multifluorophore...PHOTONICS DICTIONARY+ TERMSPhotonics Dictionaryfluorescence lifetimeFluorescence lifetime refers to the average time it takes for a fluorophore, a molecule that absorbs light at one wavelength and emits it at another, to return to its ground state after being excited...Photonics Dictionarystochastic optical reconstruction microscopyStochastic optical reconstruction microscopy (STORM) is a superresolution microscopy technique that enables imaging of biological specimens at resolutions beyond the diffraction limit of conventional...Photonics Dictionarynanoparticle photonic resonator absorption microscopyNanoparticle photonic resonator absorption microscopy is a microscopy technique that combines the principles of photonic resonators and nanoparticle imaging to visualize and study biological samples...Photonics Dictionarysingle-photon avalanche diodeA single-photon avalanche diode (SPAD) is a specialized type of photodetector designed to detect extremely weak optical signals, down to the level of single photons. 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Its unrivalled...Photonics.com 10/12/2021pco - Frequency Domain Fluorescence Lifetime Imaging Microscopy - A Hands-On SessionThis hands-on session about FD-FLIM by Gerhard Holst from PCO AG was given as part of the FLIM Symposium "Beginners Guide to Fluorescence Lifetime Imaging in Life Sciences".Photonics.com 9/28/2023Reynard CorporationReynard Corporation manufactures custom optics and thin-film coatings 0.2 µm to 50 µm (UV-IR) to demanding specs for defense & aerospace, commercial & industrial, and medical applications. Our...PHOTONICS BUYERS' GUIDE CATEGORIESAutocollimatorsAn autocollimator is an optical instrument used for measuring small angular deviations with high precision. It operates on the principle of autocollimation, where a light source is directed onto a...Infrared CollimatorsTarget ProjectorsLarge OpticsCOMPANIESPhotonics Buyers' GuideCoolLED Ltd.CoolLED designs and manufactures cutting edge LED illumination systems for researchers and clinicians using the latest LED technology. Since our team of four introduced the first commercially...Photonics Buyers' GuideShanghai Optics Inc.ISO 9001 & ISO 13485 certified and D&B DUNS # 113515303 Shanghai Optics is an unparalleled custom system solution provider offering advance precision custom optical design, engineering,...Photonics Buyers' GuideOptikos CorporationThe Optical Engineering Experts® Optikos designs and manufactures metrology products for measuring and assuring optical image quality; and provides optical engineering design, development,...Photonics Buyers' GuideOZ Optics LimitedEstablished in 1985, OZ Optics is a leading worldwide supplier of fiber optic components, test equipment and sensors. OZ Optics manufactures its products in three locations, Ottawa (Canada),...