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  • 532-nm Semiconductor Lasers
May 2010
Coherent Inc.Request Info
SANTA CLARA, Calif., May 19, 2010 — Coherent Inc. has expanded its Sapphire family of compact continuous-wave visible lasers with 532-nm green models based on proprietary optically pumped semiconductor laser (OPSL) technology.

Two models of the Sapphire 532 are being offered with a choice of either 200- or 300-mW output. They provide a high-quality TEM00 output beam characterized by low noise of 0.25% rms. Their combination of compact 125 × 70 × 34-mm packaging and low power consumption translates into easier integration and lower cost of ownership for OEM instrument builders.

The lasers have the same form, fit and function as existing Sapphire LP series models at other wavelengths such as 460, 488, 514, 561 and 568 nm, simplifying incorporation of this new wavelength into existing instrument platforms.

Most traditional continuous-wave 532-nm lasers based on Nd:YVO4 crystals suffer from higher output noise because the intracavity doubling mechanism causes a phenomenon called green noise. In contrast, the OPSL has a very short upper state lifetime that naturally eliminates green noise completely without additional measures such as complex single longitudinal mode operation. Together with their high output power, this makes these lasers suitable for fast-throughput applications based on accurate measurements of relative fluorescence intensity.

Applications span several areas of bioinstrumentation that use fluorophores optimized for 532-nm excitation, including DNA sequencing, flow cytometry, confocal microscopy and high-throughput drug discovery.


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flow cytometry
A method of measuring the characteristics of microscopic particles, usually cells, as they flow in a fluid stream through a beam of light. Particles may be stained with fluorescent dye and the fluorescence detected via laser illumination.
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