The Genesis CX355-250 laser from Coherent Inc. delivers true-CW, ultraviolet, solid-state performance, producing more than 250 mW of TEM00 output. It uses proprietary optically pumped semiconductor laser technology, providing a combination of <0.5% noise and high output power, which enables OEM instruments to achieve good signal-to-noise characteristics. The output beam has an M2 value of <1.2 to enable optimum collimation and/or refocusing to a diffraction-limited spot. Applications include flow cytometry of live cells, such as egg and fertilized-egg sorting, and high-throughput cytometers incorporating two parallel laser interaction cells. It also is suitable for other fluorescence-based applications such as confocal microscopy, where its short wavelength and low M2 beam provide optimum excitation of Hoechst and Indo dyes, and for 3-D prototyping applications, i.e., stereolithography.