The Cooke Corp. has introduced pco.edge, a camera system that performs high-fidelity scientific imaging. Based on a scientific CMOS image sensor, it delivers low noise, fast frame rates, a wide dynamic range, high quantum efficiency, high resolution and a large field of view, simultaneously and all in one image. The camera offers low readout noise of 1.4 e— rms. Even at the maximum speed of 100 fps at full resolution of 2560 x 2160 pixels (5.5 megapixels, 21.8-mm diagonal, 6.5-μm pixels), the readout noise is <2 e—. Applications include live-cell microscopy, particle imaging velocimetry, single-molecule detection, superresolution microscopy, total internal reflection fluorescence microscopy/waveguides, adaptive optics, solar astronomy, fluorescence spectroscopy, photovoltaic inspection, x-ray tomography, machine vision, spectral and hyperspectral imaging, and laser-induced breakdown spectroscopy.