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Fluorescence Imaging Microscope

BioPhotonics
Jan 2011
UVP LLCRequest Info
 
UVP LLC’s iBox Explorer fluorescence imaging microscope is for rapid high-resolution analysis of fluorescently tagged cells, tissues, organs and whole animals in the visible and near-IR wavelengths. The third in a line of in vivo systems, it offers real-time fluorescence imaging that can speed up basic and preclinical research studies of tumors and of heart and metabolic diseases. The instrument can micro-image cells and organs subcutaneously and within the body cavity of living mice. It operates through intuitive software control, using parcentered and parfocal optical configurations to enable seamless imaging through the magnification ranges. Applications include imaging whole organs, tumor/host margins and interactions, tumor microenvironment, vasculature and micrometastases.


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GLOSSARY
fluorescence
The emission of light or other electromagnetic radiation of longer wavelengths by a substance as a result of the absorption of some other radiation of shorter wavelengths, provided the emission continues only as long as the stimulus producing it is maintained. In other words, fluorescence is the luminescence that persists for less than about 10-8 s after excitation.
magnification
The ratio of the size of the image of an object to that of the object. The ratio of the linear size of the image to that of the object is lateral magnification. Angular magnification is the ratio of the apparent angular size of the image observed through an optical device to that of the object viewed by the unaided eye. Longitudinal magnification is the ratio of the longitudinal or axial dimension of an image to the corresponding dimension of the object.
microscope
An instrument consisting essentially of a tube 160 mm long, with an objective lens at the distant end and an eyepiece at the near end. The objective forms a real aerial image of the object in the focal plane of the eyepiece where it is observed by the eye. The overall magnifying power is equal to the linear magnification of the objective multiplied by the magnifying power of the eyepiece. The eyepiece can be replaced by a film to photograph the primary image, or a positive or negative relay...
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