Andor Technology plc has launched the TuCam, an adapter for simultaneous two-camera macro- and microscopic imaging. Suited to fast, concurrent detection of two different fluorophores in experiments such as colocalization Förster resonance energy transfer and ratiometric ion signaling, it is compatible with the company’s low-light imaging cameras, including iXon3 and Luca electron-multiplying CCDs, the Clara interline CCD and the Neo sCMOS model. Bypass mode and first surface mirror enable switching between cameras. It can be configured for simultaneous imaging from two similar cameras, or as a switch between camera models with different capabilities. The robust design ensures good optical and mechanical stability, and ease of alignment via kinematic cassettes. The adapter is available in C- and CSUX-mount versions and offers a variety of beamsplitting optics.