For deep tissue imaging, Spectra-Physics, a Newport Corp. brand, has released the InSight DeepSee ultrafast laser system. Based on proprietary technology, the turnkey device delivers nearly double the tuning range of existing ultrafast lasers, according to the company, and provides seamless access to long-infrared wavelengths for deep in vivo imaging. Robust and fully automated, it provides hands-free operation. It offers 680- to 1300-nm continuous tuning from a single source, short 100-fs pulse widths and high peak power levels into the infrared, where imaging penetration depth is maximized. The DeepSee dispersion pre-compensator delivers the short pulses through a microscope to the sample for maximum fluorescence. A dual-wavelength option is available for advanced imaging techniques, including uncaging, coherent anti-Stokes Raman scattering imaging and multimodal imaging.