SURREY, British Columbia, Canada, Oct. 19, 2011 — For high-speed live-cell fluorescence imaging applications, QImaging announces the Rolera Bolt scientific CMOS (sCMOS) camera. Designed for low-light applications, it is suited for biomedical imaging, as more research moves toward live-cell and whole organism studies at video frame rates. This includes motility studies where dynamic events (e.g., zebra fish heart contractions, C. elegans tracking) must be captured with high spatial and temporal resolution to provide the maximum amount of information to the researcher. The camera also is used for life sciences applications that use fluorescent labeling, such as immunofluorescence, ratiometric imaging, high-speed calcium imaging, time-lapse fluoresence and fluoresence in situ hybridization. It also performs machine vision and industrial imaging. Features include a high-quantum-efficiency 1.3-megapixel sensor with 3.63 × 3.63-µm pixel size, read noise of ~ 3 e-, and 30-fps full-resolution simultaneous readout. Using new Pixel-Freeze Technology, dark current is reduced to nearly undetectable levels, eliminating the need for an expensive Peltier cooling system. The resulting lightweight compact design, with minimal power requirements, enables the camera to use a single USB 2.0 connection for both power and 12-bit data transfer. Because of its smaller pixel size, it can be used with lower magnifications to achieve increased signal and field of view. A dynamic range of ~4500:1 allows the camera to quantitatively display dim and bright signals in a single image, a range comparable to standard CCD devices. Using the standard QCam API and proprietary software development kit, the Rolera Bolt seamlessly integrates with high-end OEM systems and customized software applications. It is backed by a two-year limited warranty and by support technicians trained in specific applications and installation procedures.