For high-speed live-cell fluorescence imaging, QImaging has announced the Rolera Bolt scientific CMOS camera. Designed for low-light applications, it is suited for biomedical imaging as more research moves toward live-cell and whole-organism studies at video frame rates. This includes motility studies where dynamic events (e.g., zebra fish heart contractions, C. elegans tracking) must be captured with high spatial and temporal resolution. The camera also is suitable for life sciences applications that use fluorescent labeling, such as immunofluorescence, ratiometric imaging, high-speed calcium imaging, time-lapse fluorescence and fluorescence in situ hybridization. It also performs machine vision and industrial imaging. Features include a high-quantum-efficiency 1.3-megapixel sensor with 3.63 x 3.63-µm pixel size, read noise of about 3 e— and 30-fps full-resolution simultaneous readout.