Leica Microsystems GmbH's SCN400 and SCN400 F line scanners capture the largest area in digital pathology. This release in the company's total digital pathology portfolio provides a new level of flexibility, enabling the scanning of a wide range of samples on a single system. The scanners can capture traditional 26 x 76-mm, double 52 x 76-mm and now jumbo 113 x 76-mm slides in either bright field or fluorescence. Users of the SCN400 digital slide scanner range can implement large slide scanning without hardware changes or physical updates to their scanners. This advancement is suitable for research in neuroscience, toxicological pathology and for anyone dealing with large tissue sections.