The WSKM incubation system from Prior Scientific Inc. provides a compact, long-term stable environment for live-cell imaging. Designed to work with the company’s ProScan H117 flattop stages, it positions the sample in the proper focus for maximum microscope functionality. The chamber unit is set up to handle various types of microtiter/well plates from six up to 96 wells. Other applicable dishes, including 35-, 50- and 60-mm petri dishes, chamber slides and chambered cover glass, can be used with the purchase of adapter inserts. The base controller included with the WP1154 INUBTFP-WSKM system controls temperature only. The WP1155 INUBTFPWSKM-F1 includes control for temperature and premixed gas, providing a constant temperature and CO2-enriched environment that extends the life of the growth medium during prolonged experiments.