The largest capture area of any line scanner in digital pathology is now possible with the Leica SCN400 and SCN400 F, according to Leica Microsystems GmbH. The new release in the company’s total digital pathology portfolio enables digitization of very large specimens, providing flexibility and enabling the scanning of a wide range of samples on a single system. The scanners can capture traditional 26 x 76-mm, double 52 x 76-mm and now jumbo 113 x 76-mm slides in either bright-field or fluorescence. Users of the SCN400 digital slide scanner range can implement large slide scanning without hardware changes or physical updates to their scanners. The advance has applications in neuroscience and toxicological pathology.