For high-speed live-cell fluorescence imaging applications, QImaging announces the Rolera Bolt scientific CMOS camera. Designed for low-light applications, it is suitable for biomedical imaging as more research moves toward live-cell and whole-organism studies at video frame rates. This includes motility studies where dynamic events (e.g., zebra fish heart contractions, C. elegans tracking) must be captured with high spatial and temporal resolution to provide the maximum amount of information to the researcher. The camera also is used for life sciences applications that employ fluorescence labeling, such as immunofluorescence, ratiometric imaging, high-speed calcium imaging, time-lapse fluoresence and fluoresence in situ hybridization. Features include a high-quantum-efficiency 1.3-megapixel sensor with 3.63 x 3.63-µm pixel size, read noise of ~ 3e—, and 30-fps full-resolution simultaneous readout.