WETZLAR, Germany, June 5, 2012 — Leica Microsystems has launched the DM4000 B LED, a microscope system with innovative LED illumination suited for biomedical routine and research applications. The LED transmitted light illumination solution is integrated into the microscope automation to produce constant color temperature at all intensity levels without heat buildup and to produce stable results. High luminance and optimal color reproduction provide high-quality images with a clear differentiation of the colors in the sample. With at least a 50,000-h lifetime, the LED illumination is cost-effective, and frequent bulb changes are not necessary. The microscope sets parameters for transmitted light and fluorescence illumination according to the user’s selection of contrast method and magnification. Most recently used settings are stored and recalled automatically. The fully automated fluorescence axis with apochromatic light path provides bright images with high contrast. Intelligent automation also means high-quality, publication-ready images and maximum reproducibility for reliable data analysis. The instrument is suited for clinical pathology applications with H&E- or IHC-stained slides. Its transmitted light modes may be adjusted according to applications and user preferences. Repetitive movements are reduced because of the ergonomic design. The Leica Application Suite software package fully integrates the Leica DM4000 B LED microscope and digital camera into an optimized system for visualization, storage and documentation of microscope images.