SUNNYVALE, Calif., Dec. 10, 2012 — Molecular Devices LLC has released the MetaMorph superresolution system with synchronized image acquisition and processing, enabling analysis of object details smaller than 250 nm in fixed and live cells. It features real-time image processing, expanding the capabilities of optical microscopy in research. It supports scientific applications from time-lapse studies to 3-D investigations. Using light microscopy alone, images of biological matter smaller than 250 nm appear blurred and are virtually impossible to analyze. Superresolution microscopy helps to overcome these limits by reconstructing images at a resolution surpassing the diffraction limit of the objective lens. With patent-pending image processing techniques, the system produces 20-nm lateral resolution in real time. It builds on the MetaMorph software that guides researchers through setup, acquisition and analysis, with a dedicated workspace in the user interface ensuring that relevant configuration and display settings are accessible. Side-by-side displays and image statistics provide a multifaceted view of the quality and progress of image acquisition and processing. A hardware acceleration component supports fast acquisition and analysis with real-time superresolution image display. An optional off-line mode allows superresolution processing of previously acquired images. The system is compatible with most fluorescence and total internal reflectance fluorescence microscopes.