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Digital Slide Scanner

Photonics.com
Dec 2012
Carl Zeiss Spectroscopy GmbHRequest Info
 
JENA, Germany, Dec. 24, 2012 — The Microscopy business group of Carl Zeiss is launching a digital slide scanner. Axio Scan.Z1 is an automated microscope system that allows researchers to digitize fixed tissue sections and cytologic specimens in bright-field and fluorescence applications.

Thanks to the tray concept, the scanner captures the entire specimen area of the microscope slide, including the edge. A few minutes later, the self-calibrating automatic slide scanner presents specimens on high-quality virtual slides. Up to 100 microscope slides can be digitized at a time. For fluorescence applications, filter wheels switch wavelengths in 50 ms. Sensitive cameras and maximally corrected optics achieve optimal image quality. The Colibri.2 UV-free LED light source and a focus finder with oblique illumination, the ring aperture contrast, ensure maximum protection for the sample.

Applications include tissue analysis in Alzheimer’s disease, cancer research and the pharmaceutical industry.

Axio Scan.Z1 is operated by proprietary ZEN imaging software, which allows users to work with predefined recording parameters automatically or to select all settings individually.

The virtual slides are organized in the ZEN Browser web-based database. Independent of the operating system, users can access, view and share their images and data with colleagues online and organize entire projects, even while traveling. There is also a free app for iPad and iPhone to facilitate this.

Users can decide how many microscope slides and which detection modes and camera they wish to use, and can upgrade Axio Scan.Z1 as their tasks expand.


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GLOSSARY
fluorescence
The emission of light or other electromagnetic radiation of longer wavelengths by a substance as a result of the absorption of some other radiation of shorter wavelengths, provided the emission continues only as long as the stimulus producing it is maintained. In other words, fluorescence is the luminescence that persists for less than about 10-8 s after excitation.
microscope
An instrument consisting essentially of a tube 160 mm long, with an objective lens at the distant end and an eyepiece at the near end. The objective forms a real aerial image of the object in the focal plane of the eyepiece where it is observed by the eye. The overall magnifying power is equal to the linear magnification of the objective multiplied by the magnifying power of the eyepiece. The eyepiece can be replaced by a film to photograph the primary image, or a positive or negative relay...
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