Request InfoCarl Zeiss Spectroscopy GmbHZeiss has added the Elyra P.1 module to its 3-D microscopy portfolio. The system enables superresolution photoactivated localization microscopy (PALM) for endogenously expressed photoswitchable fluorescent proteins. This capability allows researchers to investigate the structural arrangement of one or multiple proteins, reveal the structure of organelles in 2-D and 3-D, and count and map molecules within a structure. In PALM, photoswitchable fluorescent molecules are sparsely activated so that only one out of many will be in its “on” state within a single point spread...See full productRelated content from Photonics MediaPRODUCTSBioPhotonics Mar/Apr 2024 IssueSuperresolution SIM MicroscopesThe Lattice SIM 3 and Lattice SIM 5 from ZEISS are superresolution microscopes that use structured illumination microscopy (SIM) to overcome the physical resolution limits of light microscopy. Along...Promoted Content June 2023 IssueNanopositioning for High-Res MicroscopyPI's new Fast Focus Stages and Multi-Axis Piezo Flexure Scanners for Microscopy are designed to improve the performance of high-resolution microscopy. Choice of piezo and voice coil motors....BioPhotonics Mar/Apr 2023 IssueCell Imaging SystemThe Axiovert 5 cell imaging system from ZEISS uses artificial intelligence and automatic functions to ease daily work in the cell lab. From scientific routine and basic research to phase...BioPhotonics Nov/Dec 2023 IssueMicrosurgery Digital MicroscopeThe PENTERO® 800 S from ZEISS is a digital microscope used for microsurgery with spines, neurosurgery, and reconstructive surgery. Offering extended optical capabilities, the system offers visual...ARTICLESPhotonics.com 2/23/2024SPAD Elevates Spatiotemporal Resolution in Conventional MicroscopesImage scanning microscopy (ISM), a superresolution technique enabled by the advent of fast and compact detector arrays, provides signal-to-noise ratio (SNR), optical sectioning, and spatial...Photonics Spectra February 2024 IssueAlgorithm Boosts Live-Cell Imaging's CapabilitiesSuperresolution radial fluctuations (SRRF), a superresolution algorithm, works by observing fluctuations in radial symmetry throughout the frames of an image. SRRF supports live-cell, superresolution...Photonics Spectra January 2024 IssueVirtual Superlens Passes Diffraction Limit Without DistortionThe diffraction limit enforces physical restrictions on how closely an object can be examined using traditional optical methods. Previous attempts to develop superlenses that image beyond the...BioPhotonics Sep/Oct 2023 IssueDNA-Barcoded Fluorescence Imaging Illuminates Core Cell ComponentsSince many core components of cells — like DNA, RNA, proteins, and lipids — are just a few nanometers in size and substantially smaller than the resolution limit of traditional light...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookSuperresolution Microscopy: An Imaging RevolutionSuperresolution optical microscopy, for which the Nobel Prize was awarded to Eric Betzig, Stefan Hell, and William Moerner in 2014, has been one of the most momentous developments in the life...Photonics HandbookLasers for Microscopy: Major TrendsLaser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and...Photonics HandbookNanopositioning: A Step AheadBy its original definition, a nanopositioning device is a mechanism capable of repeatedly delivering motion in increments as small as one nanometer. Lately demands from industry and research have...Photonics HandbookAspheric Lenses: Design ConsiderationsAspheric surfaces are powerful tools that combine the optical corrections of multiple lenses into a single element (Figure 1) and affect performance in ways that spherical optics cannot. For example,...WHITEPAPERSPhotonics.com 10/4/2022Product Development Strategies for Electro-Optical SystemsThis whitepaper looks at the unique challenges associated with optical systems by exploring two extremes, an ultra-high precision instrument, and a low-cost consumer product, and the different...Photonics.com 4/28/2023“Fingerprint” vs Handheld Raman Applications and the Different Optical Filters That Enable ThemRaman spectroscopy is a powerful non-invasive, non-contact tool capable of identifying molecular constituents of samples. Wavelength selective optical filters are used to block the dominant Rayleigh...Photonics.com 2/16/2024Rapid Automated Modular MicroscopeOverview of Rapid Automated Modular Microscope.Photonics.com 1/10/2024Single-Objective Light SheetAn overview of the Single-Objective Light Sheet.WEBINARSPhotonics.com 10/24/2023Adaptive Optics in Microscopy: Practical Use of Wavefront Correctors and Control MethodsAdaptive optics can be used to correct for instrument and sample aberrations or to dynamically shape the wavefront and point spread function (PSF) to create new possibilities or reduce instrument...Photonics.com 1/19/2022Next-Generation Optics Software: Trends in TechnologyPhysical optics calculation software typically provides a single solving program for Maxwell’s equations. Field solvers such as finite difference time domain (FDTD) or the finite element method...Photonics.com 8/17/2022Sub-Cellular Biology at Tissue Scales with Cleared Tissue Axially Swept Light-Sheet MicroscopyLarge-scale interdisciplinary research efforts have worked to comprehensively catalog cellular architectures in health and disease. To aid in this effort, researchers have developed a scalable...Photonics.com 3/21/2013Techniques in Biophotonic ImagingFREE WEBINAR Sponsored by: Hamamatsu & Applied Scientific Instrumentation Additional Questions & Answers from the webinar are below: Dr. Kimani C. Toussaint Jr. Quantitative...PHOTONICS DICTIONARY+ TERMSPhotonics DictionarysuperresolutionSuperresolution refers to the enhancement or improvement of the spatial resolution beyond the conventional limits imposed by the diffraction of light. In the context of imaging, it is a set of...Photonics DictionarySTED microscopySTED microscopy, or stimulated emission depletion microscopy, is a super-resolution imaging technique in fluorescence microscopy that surpasses the diffraction limit, enabling the visualization of...Photonics Dictionarypoint spread functionThe point spread function (PSF) is a fundamental concept in imaging that describes the response of an imaging system to a point source or point object. It characterizes how a single point of light is...Photonics Dictionarysingle molecule localization microscopySingle molecule localization microscopy (SMLM) is a group of super-resolution microscopy techniques that surpass the diffraction limit of traditional optical microscopes, allowing for the...VIDEOSPhotonics.com 1/18/2018Supporting the Photonics Industry from the Laboratory - LIGHT MATTERS 01.2018On this month's episode of Light Matters, we take you to central Massachusetts as Worcester Polytechnic Institute and Quinsigamond Community College take on a comprehensive joint photonics laboratory...Photonics.com 1/18/2018Light Matters Extra: Taking Photonics Innovations from the Lab to the Operating Room - 01.2018In this month's Light Matters Extra, we give you an in-depth look at the relationship between researchers and scientists at the University of California Davis, and surgeons and clinicians at nearby...Photonics.com 4/19/2022Optolong Fluorescence Filter Set Comparation FITC/DAPI/TexasRed - Optolong Optics Co. Ltd.Fluorescent filter is a key component of biomedical and life science instruments, and its main function is to separate and select the characteristic band spectra of excitation light and emission...Photonics.com 11/20/2023New Dragonfly 600 Confocal Microscope System - Andor TechnologyThe Dragonfly 600 confocal microscope system delivers outstanding multi-dimensional images from subcellular (nm) to whole organism (cm), while significantly boosting productivity. Its unrivalled...PHOTONICS BUYERS' GUIDE CATEGORIESSuperresolution Imaging SystemsUltraviolet MicroscopesAn ultraviolet microscope is a microscope used either to detect selective absorption of various wavelengths by the specimen or to achieve increased resolution by virtue of the short wavelength of...Microscope LensesBioluminescence MicroscopesCOMPANIESPhotonics Buyers' GuideCarl Zeiss Spectroscopy GmbHCarl Zeiss Spectroscopy develops and produces optical gratings, optical modules, and spectrometer systems of highest quality, superior optical performance, robust design and fast analysis. We...Photonics Buyers' GuideFOCtek Photonics Inc.FOCtek provides customers with all types of custom manufactured lenses, Precision Optical Components, Polarizing Optics, Prisms, Filters, Coatings, Optical Systems, Crystals, Nonlinear Crystals,...Photonics Buyers' GuideCASTECH INC.CASTECH is a recognized leading supplier of nonlinear optical crystals, laser crystals and precision optical components for laser, telecom, medical, analysis and detector markets. Products...Photonics Buyers' GuideReynard CorporationReynard Corporation has been a premier supplier of custom optics and thin-film coatings to a global customer base since 1984. Reynard focuses on manufacturing the highest quality products with...