USB 3.0 camera platform by Andor Technology Ltd. operates at up to 53 fps from a 4.2-megapixel array, offering low read noise and a wide dynamic range. The high-bandwidth plug-and-play USB 3.0 interface is available on the Zyla 5.5 and 4.2 models, which house 5.5- and 4.2-megapixel sensors, respectively. Their light, low-vibration design is suited for research and OEM usage. Comprehensive on-head field-programmable gate array real-time data processing enhances image quality and stability. These scientific CMOS models are compatible with microscopy applications including ion signaling, superresolution and light sheet.