WALTHAM, Mass., Nov. 13, 2014 — New 10× and 25× microscope objectives from Olympus Scientific Solutions Americas are optimized for deep, high-resolution imaging of life science specimens up to 8mm beneath the surface. The objectives are designed for multiphoton imaging using clearing techniques such as Clarity, Scaleview and SeeDB, along with live-cell imaging and light-sheet microscopy. They can be employed to combine conventional multicolor two- and three-photon imaging with label-free methods such as third- and second-harmonic generation. The objectives feature a transmittance range of 400 to 1600 nm, allowing deeper imaging with minimal damage to tissue. A field number of 27.5 provides excellent scattered-light collecting abilities and a large field of view (1.8mm at 10×) enhances data collection. Compatible with Olympus multiphoton imaging systems and custom-built light-sheet and other single-plane illumination microscopes, the objectives can handle immersion in water, clearing reagents and silicone oil.