Request InfoPicoQuant GmbHThe combination of atomic force microscopy (AFM) with time-resolved single-molecule-sensitive fluorescence microscopy in a single instrument opens up new avenues for fascinating investigations into the structure, dynamics, and interactions of single molecules or their assemblies in cells or tissue samples. The time-resolved microscopy platform MicroTime 200 from PicoQuant can be interfaced with a series of AFMs from Bruker, JPK, and Asylum Research while maintaining its full range of capabilities, such as super-resolution via Stimulated Emission Depletion (STED) or performing Fluorescence...See full productRelated content from Photonics MediaPRODUCTSPromoted Content October 2022 IssueXYZ Nanopositioners for MicroscopyThe Nano-LPS and Nano-LPQ are ultra-low profile 3-axis nanopositioning systems with sub-nanometer precision under closed loop control. These piezo nanopositioners incorporate our exclusive PicoQ®...Promoted Content June 2023 IssueNanopositioning for High-Res MicroscopyPI's new Fast Focus Stages and Multi-Axis Piezo Flexure Scanners for Microscopy are designed to improve the performance of high-resolution microscopy. Choice of piezo and voice coil motors....Promoted Content March 2023 IssueMad City Labs GmbH - Tools for the NanoscaleMad City Labs provides tools for the nanoscale for applications in photonics, microscopy, and physics. Our portfolio includes closed loop piezo nanopositioners, micropositioners, atomic force...Photonics Showcase November 2023 IssueQS-PLL™ AFM ControllerThe QS-PLL™ AFM controller is designed for use with AFM resonant probes. The high sensitivity of resonant probes makes it ideal for applications such as scanning NV magnetometry and quantum...ARTICLESPhotonics.com 4/20/2022Rotating Laser Enables Faster, Longer Imaging of CellsA microscopy method developed at the University of Freiburg is able to resolve cellular-level detail without fluorescence, enabling observations 100 to 1000× longer and 10 to 100× times...BioPhotonics Sep/Oct 2022 IssueSignal Sorting Method Suppresses Noise in STED MicroscopyResearchers from Zhejiang University have proposed a novel microscopy method that selectively and effectively suppresses background noise in the existing technique of stimulated emission depletion...BioPhotonics Jul/Aug 2023 IssueCentury-Old Effect Applied for Study of Embryonic DevelopmentResearchers have applied line-scanning Brillouin microscopy (LSBM), a microscopy technique based on Brillouin scattering, to visualize the mechanical properties of living cells over space and time,...Photonics.com 5/5/2022Internal Reflection-Based Microscopy Images Single ProteinA team from Arizona State University (ASU) has introduced evanescent scattering microscopy (ESM), a label-free method for sensitive imaging of biomolecules, including proteins. The single-molecule...PHOTONICS HANDBOOK ARTICLESPhotonics HandbookSuperresolution Microscopy: An Imaging RevolutionSuperresolution optical microscopy, for which the Nobel Prize was awarded to Eric Betzig, Stefan Hell, and William Moerner in 2014, has been one of the most momentous developments in the life...Photonics HandbookFluorescence Lifetime Imaging: Choosing the Best ApproachThe term fluorescence is often applied as a synonym for photoluminescence, although luminescence actually covers fluorescence and phosphorescence. Both of these terms describe the process of...Photonics HandbookNSOM: Discovering New WorldsNSOM is suitable for studies on the mesoscopic scale (several tens to hundreds of molecular dimensions). It has become an important tool in research and applications of semiconductors, organic layers...Photonics HandbookMeasuring Surface Roughness: The Benefits of Laser Confocal MicroscopyWhen evaluating the surface of a component, surface roughness can be assessed by eye or by rubbing it with a fingertip. Common expressions include “shiny,” “lusterless and...WHITEPAPERSPhotonics.com 4/20/2023Is a DIY Microscope for You?For some advanced microscopy and nanoscopy techniques it becomes necessary to modify existing instrumentation or build an instrument from scratch. This article helps readers determine whether a...Photonics.com 11/21/2023Conceptualizing Super-Resolution Microscopy eBookA clever way to overcome the limitation caused by diffraction is to use 'pointillism strategy', a concept introduced by Rainer Heintzmann in 2005. The idea is to have only one fluorescent emitter...Photonics.com 10/19/2023Clean, New Bioenergy Sources: One Molecule at a TimeResearchers at Penn State University are spearheading a multidisciplinary research effort to explore ways to produce bioethanol more efficiently from lignocellulose. Importantly, this is not corn...Photonics.com 2/28/2024Multi-Bandpass Filters for FluorescenceLearn how multi-bandpass filters combined with multiple LEDs can enable versatile and compact fluorescence instrumentation.WEBINARSPhotonics.com 1/24/2019Advances in Rapid 3D Imaging of Large Tissue SamplesThis webinar will discuss rapid 3D, multiplexed imaging of large tissue samples, based on recent advances in light-sheet fluorescence microscopy, multiplexed molecular labeling, and optical tissue...Photonics.com 1/21/2021Rapid and Effective Large-Area Raman Imaging: Raman Microscopy EvolvesThe last 25 years have seen Raman microscopy evolve from a relatively slow spectroscopic imaging technique, which could take days to image a sample, to an accepted rapid and powerful technique. It is...Photonics.com 1/21/2021Correlative 3D Raman Imaging: The Sample Characterization MultitoolConfocal Raman imaging is a powerful, versatile, and increasingly common microscopy technique capable of quickly identifying the molecules in a sample and visualizing their physical distribution...Photonics.com 10/14/2021Raman Imaging for the Complete Polymer Lifecycle: From Materials Science to Environmental ImpactPolymers are omnipresent in contemporary products such as coatings and packaging. They begin as chemical formulations optimized for specific functions, are produced at-scale while being checked for...PHOTONICS DICTIONARY+ TERMSPhotonics Dictionaryoptical tweezersOptical tweezers refer to a scientific instrument that uses the pressure of laser light to trap and manipulate microscopic objects, such as particles or biological cells, in three dimensions. This...Photonics Dictionarystochastic optical reconstruction microscopyStochastic optical reconstruction microscopy (STORM) is a super-resolution microscopy technique that enables imaging of biological specimens at resolutions beyond the diffraction limit of...Photonics DictionarysuperresolutionSuperresolution refers to the enhancement or improvement of the spatial resolution beyond the conventional limits imposed by the diffraction of light. In the context of imaging, it is a set of...Photonics Dictionarykinetic coolingAn atmospheric nonlinear process unique to CO2 laser wavelengths, whereby CO2 absorbs 10.6-µm radiation and the CO2 molecules in the (100) vibrational state are excited to the (001) level, and...VIDEOSPhotonics.com 11/20/2023Andor's Life Science Research SolutionsAt Andor, it matters to us that the products we develop make a real difference to our customers and contribute significantly to their research across Immunology, Microbiology, Neuroscience, Cells &...Photonics.com 11/20/2023Andor OEM IntegrationsCutting-edge Innovation √ Unparalleled Quality √ Designed-in Reliability √ Custom Designs √ Andor is the trusted choice for OEM integrations, supplying cameras, spectrographs,...Photonics.com 11/20/2023New ZL41 Cell & Sona sCMOS - Easy, Flexible, Cost-Effective Super Resolution Microscopy - Andor TechnologyEasy and Cost-Effective Super-Resolution to ~100 nm. Andor has introduced two new highly innovative sCMOS cameras, both delivering easy and cost-effective access to super-resolution capabilities and...Photonics.com 11/20/2023New Dragonfly 600 Confocal Microscope System - Andor TechnologyThe Dragonfly 600 confocal microscope system delivers outstanding multi-dimensional images from subcellular (nm) to whole organism (cm), while significantly boosting productivity. Its unrivalled...PHOTONICS BUYERS' GUIDE CATEGORIESMicroscopy NanotechnologyAtomic Force MicroscopesAn atomic-force microscope is a type of microscope that produces a quantitative, three-dimensional image of the surface of a sample. The surface is scanned by an extremely sharp tip mounted to a...Scanning Probe MicroscopesForensic MicroscopesCOMPANIESPhotonics Buyers' GuideMad City Labs Inc.Mad City Labs, Inc. is a leading manufacturer of piezo nanopositioning systems and instrumentation capable of sub-nanometer positioning resolution. Our product line of nanopositioners,...Photonics Buyers' GuideBruker Nano SurfacesBruker Nano Surfaces is a leading provider of high-performance scientific instruments and solutions for molecular and materials research, as well as for industrial and applied analysis. We cover...Photonics Buyers' GuideArkwright Technologies Pty. Ltd.Arkwright Technologies design and manufacture application specific fiber Bragg grating (FBG) sensors. Our innovative, award winning designs have evolved from over 30 years direct expertise in the...Photonics Buyers' GuideAndor TechnologyAndor Technology Ltd is a global developer and manufacturer of high-performance scientific cameras, microscopy systems and spectrographs for academic, government, and industrial applications. Founded...